ID A0A1H1B2F7_9ACTN Unreviewed; 634 AA.
AC A0A1H1B2F7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Succinate dehydrogenase / fumarate reductase flavoprotein subunit {ECO:0000313|EMBL:SDQ46128.1};
GN ORFNames=SAMN04489764_0768 {ECO:0000313|EMBL:SDQ46128.1};
OS Thermostaphylospora chromogena.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermostaphylospora.
OX NCBI_TaxID=35622 {ECO:0000313|EMBL:SDQ46128.1, ECO:0000313|Proteomes:UP000217103};
RN [1] {ECO:0000313|EMBL:SDQ46128.1, ECO:0000313|Proteomes:UP000217103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43794 {ECO:0000313|EMBL:SDQ46128.1,
RC ECO:0000313|Proteomes:UP000217103};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNKK01000002; SDQ46128.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1B2F7; -.
DR STRING; 35622.SAMN04489764_0768; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000217103; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF89; SUCCINATE DEHYDROGENASE [IRON-SULFUR SUBUNIT] (SUCCINIC DEHYDROGENASE)-RELATED; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000217103}.
FT DOMAIN 9..428
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 482..574
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 321
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 634 AA; 69762 MW; 2AEB5F34F02E7123 CRC64;
MEIERHQYDV VVIGAGGAGL RAAIEARQQG KKTAIVCKSL FGKAHTVMAE GGAAAAMGNV
NPADNWKVHF RDTMRGGKFL NNWRMAELHA KEAPDRVWEL EAWGALFDRT KDGKISQRNF
GGHEYPRLAH VGDRTGLEMI RTLQQRVVAL QQEDYATHGD YEAYIKVFAE CTITRLLKDG
NAIAGAFGYR RENGAFIVFE APAVVLATGG IGKSYTVTSN SWEYTGDGHA LALLAGAKLI
NMEFIQFHPT GMVWPPSVRG ILVTESVRGD GGVLRNSEGK RFMFDYIPEV FKAQYATTEE
EADRWYTDQA NNRRPPELLP RDEVARAINA EVKAGRGSPH GGVFLDVSTR LPAEEIRRRL
PSMYHQFKEL ADVDITAEPM QVGPTCHYIM GGVEVDADTA ASSVPGLFAA GEVAGGMHGS
NRLGGNSLSD LLVFGRRAGA GAAAYVDRLQ RRPRVNDESV AAAMDEALAP LGRTGENPYE
VHHELQRTMN DLVGIIRKED EMTEALEVVG KLKERAKGVG AAGSRVYNPG WHLCLDLRNM
LLVSECVARA ALTRTESRGG HTRDDYPGMS PEWRRKLLQC SLSPDGQTIT VEEKIQPQMR
PDLFTLFDKE ELAKYVTEEE LAEYDAAVAA VKES
//
