ID A0A1H1BPH7_9BURK Unreviewed; 599 AA.
AC A0A1H1BPH7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=H+/Cl-antiporter ClcA {ECO:0000313|EMBL:SDQ53828.1};
GN ORFNames=SAMN05443245_1751 {ECO:0000313|EMBL:SDQ53828.1};
OS Paraburkholderia fungorum.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=134537 {ECO:0000313|EMBL:SDQ53828.1, ECO:0000313|Proteomes:UP000183487};
RN [1] {ECO:0000313|Proteomes:UP000183487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS106B {ECO:0000313|Proteomes:UP000183487};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNKP01000001; SDQ53828.1; -; Genomic_DNA.
DR RefSeq; WP_074763923.1; NZ_FNKP01000001.1.
DR AlphaFoldDB; A0A1H1BPH7; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000183487; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 515..573
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 599 AA; 63577 MW; 9F5B196FF958D938 CRC64;
MSMDSHKRDF AANARLPGIF VLAACIGAVS TLAAFVLLNL IHLFTNLFFF GTLSFAERSP
AGNTLGLWVI GVPVAGGLIV GLMARFGSEK IRGHGIPEAI EAILFGKSRM SPKVAVLKPL
SSGIVIGSGG PFGAEGPIIM TGGALGSLIA QCVKVTAAER KTLLVAGAAA GMTAVFGTPV
AAVLLAVELL LFEWRPRSFL PVAIACAVAG FARALFFGTG PLFPLETAAP DSWALLSCVI
AGLLSGALAS GLSAALYKTE DLFGKLPIHW MWWPALGGIV VGIGGWLEPR ALGVGYDVIG
DLLHQHIALQ IALALLAVKA VMWVVALGSG TSGGVLAPLL MLGAGLGTVL SHWLPGNQPA
LWPLVCMAAT LGATLGAPLT AIVFTFGLTH DANALLPLLT ATLIAHGFSA VVMRRSIMTE
KIARRGYHIY REYGVDPLER HFVDEVMTPT VDSIDAGATV GETLQKFFGA NQTRRAYPVL
RDDAVIGVAD RALLEQFCRE NAEVKRAALL ADVFAQMSPT YALPSETCRL VATRLAVHNL
ERLPVVEDRK SMRLVGIVSR SDLVKPSLSH FEEEHKRERF RRLTPVLGKR RFAPIRKAG
//
