ID   A0A1H1BY27_9ACTN        Unreviewed;       676 AA.
AC   A0A1H1BY27;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Prolyl oligopeptidase {ECO:0000313|EMBL:SDQ56857.1};
GN   ORFNames=SAMN04489765_0919 {ECO:0000313|EMBL:SDQ56857.1};
OS   Tsukamurella pulmonis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC   Tsukamurella.
OX   NCBI_TaxID=47312 {ECO:0000313|EMBL:SDQ56857.1, ECO:0000313|Proteomes:UP000183053};
RN   [1] {ECO:0000313|Proteomes:UP000183053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44142 {ECO:0000313|Proteomes:UP000183053};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNLF01000002; SDQ56857.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1BY27; -.
DR   STRING; 47312.SAMN04489765_0919; -.
DR   OrthoDB; 9801421at2; -.
DR   Proteomes; UP000183053; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   PANTHER; PTHR42881; PROLYL ENDOPEPTIDASE; 1.
DR   PANTHER; PTHR42881:SF13; PROLYL ENDOPEPTIDASE; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
PE   4: Predicted;
FT   DOMAIN          2..393
FT                   /note="Peptidase S9A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02897"
FT   DOMAIN          468..672
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   676 AA;  74914 MW;  F626E49667787750 CRC64;
     MDQYAWLEEV ESATALDWAR EQGAASTARL AGPRFDEIRS GVLAILDTDQ RIPYPVRRGE
     YLWNFWRDAD HPYGLWRRTT LESFRSESPE WDVVIDVDAL REAEGENWVW GGAAVLRGVS
     PDGARYDRAL VSLSRGGADA SVVREFSISR REFLDDGFSL PEAKSRISWI DADTVYVGTD
     FGPGSLTDSG YPRLVKRWRR GTPLGHADLV YEGHHTDVSI GAGYDDTPGY ERHFVTRAID
     FYNSEIYLLD PETLALERID VPTDADADVH ESRLMVRPKS PWELPTGTVP PGALVAFDFD
     AYRSGSRDYS TVFTPDAHTA LAGYAWTKSY LLLSTMRDVR SELHTLEPGT WDERGTRGFP
     ELAEIGVYYT DPREGDEIFA TASGFTLPPT LLHGEAGGSV EPLKSAPAFY DAEGVTTEQF
     FATSDDGTQV PYFVVRKPAT GPQPTLLYGY GGFEVSLTPD YTPVSGLSWI ERGGVYVLAN
     IRGGGEYGPD WHTAALKENR LRAYEDFAAV ARDLVARGIT TREQLGAQGG SNGGLLMGVM
     YTRYPELFGA IVCQVPLLDM RRYHQLLAGA SWMAEYGDPD DPAQWAYISE YSPYQNLPSP
     DADLPALLVT TSTRDDRVHP GHARKFVAAL RERGIEVDYY ENIEGGHGGA ADNKQAAFKS
     ALAYEFLWRE LGSAES
//