ID   A0A1H1CLR3_9ACTN        Unreviewed;       808 AA.
AC   A0A1H1CLR3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=IclR helix-turn-helix domain-containing protein {ECO:0000313|EMBL:SDQ65201.1};
GN   ORFNames=SAMN05428996_2245 {ECO:0000313|EMBL:SDQ65201.1};
OS   Quadrisphaera sp. DSM 44207.
OC   Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC   Quadrisphaera.
OX   NCBI_TaxID=1881057 {ECO:0000313|EMBL:SDQ65201.1, ECO:0000313|Proteomes:UP000199015};
RN   [1] {ECO:0000313|EMBL:SDQ65201.1, ECO:0000313|Proteomes:UP000199015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44207 {ECO:0000313|EMBL:SDQ65201.1,
RC   ECO:0000313|Proteomes:UP000199015};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNKA01000003; SDQ65201.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1CLR3; -.
DR   STRING; 1881057.SAMN05428996_2245; -.
DR   Proteomes; UP000199015; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR032830; XPB/Ssl2_N.
DR   Pfam; PF13625; Helicase_C_3; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199015}.
FT   DOMAIN          65..103
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|Pfam:PF09339"
FT   DOMAIN          503..624
FT                   /note="Helicase XPB/Ssl2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13625"
FT   REGION          658..685
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          700..735
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..674
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   808 AA;  83157 MW;  7B4AB327A49FCD86 CRC64;
     MPARTSSPRS LAEDLRSRDD AALGALLRSR PDLATPVPAD TASLAARAST RVSVQRALDR
     LPTPALQVLQ ALAALPEPVP LADLARACDA PLPAVRRVVE DLRVRALVWG GERALHVVRA
     VPDVLGPAPA GLGPPLRDAL GTRSPARVAA LAADLGLEPS GDPVADLDAV AALLGDPQRL
     ERLLADAPPA ARELLDRLAW GPPTGAVEHA ERPVSTARAS TPLEWLLARG LLAAAGPSSV
     VLPREVAVAL RGGRVLAGLD DEPPPLATTS RRPDLVDGTA AGAAAEAVRL VEELLQGWSA
     APPPVLRAGG LGVRELRRVA DRLEVDAEQA AFVVELARFA GLAADDGEAD AAWAPTPAFD
     DWRAQEVPQR WGLLASSWLR TSRVPALVGE KDARGVARTA LADDLDRTSA PLVRRVVLDE
     LAQLPPGAAA DAEGLAARVR WRAPRRAGAL AGRLVGWTLR EAAWLGVTGA GALSTAGRHV
     VAEDADAAAA ALAAVLPAPV EAVLLQADLT AVAPGPLVPA LAAQMALVAD VDSRGGATVY
     RFTPASVRRA LDAGRGAADV LAFLAAHSST PVPQPLEYLV ADVARRHGRV RVGVAGSYLR
     SDDEAQLAEV VADRRAAPLR LRLLAPTVAA AQADPPAVLE ALRAMGLAPA VEGADADLVL
     RRPREHRSPP RERPRPVTGE PPAALPTLVD AVVRALRAGD AGDEPAGAGR GGAGGRDGGS
     GRSARDGGGR GGPPVLAATE PAVALEALRE AAASHRSLWV GLTDRTGRTS VRLVEPVTVE
     GGMVTALDAA SGQVRTMSVH RVTGVAPA
//