ID   A0A1H1CWW3_9MICC        Unreviewed;       684 AA.
AC   A0A1H1CWW3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:SDQ68056.1};
GN   ORFNames=SAMN04489742_2106 {ECO:0000313|EMBL:SDQ68056.1};
OS   Arthrobacter crystallopoietes.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Arthrobacter.
OX   NCBI_TaxID=37928 {ECO:0000313|EMBL:SDQ68056.1, ECO:0000313|Proteomes:UP000181917};
RN   [1] {ECO:0000313|EMBL:SDQ68056.1, ECO:0000313|Proteomes:UP000181917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20117 {ECO:0000313|EMBL:SDQ68056.1,
RC   ECO:0000313|Proteomes:UP000181917};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNKH01000002; SDQ68056.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1CWW3; -.
DR   STRING; 37928.SAMN04489742_2106; -.
DR   Proteomes; UP000181917; Unassembled WGS sequence.
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR005914; Acac_CoA_synth.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR   PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000181917}.
FT   DOMAIN          50..106
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          126..492
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   684 AA;  75220 MW;  2CE155B0DB1C8224 CRC64;
     MTDRNHPASG EPESLPRLLR EPAPDVLEKT FLGDYLRWVR QHRGLRFGSY EDLQRWSVRD
     LDAFWSSIWD YFQIRDHGSY ERALSDPRMP GARWFEGSLI NYAENALLGV GRTAPGPRSG
     GDDADTAIIG ISQTRGQIEL SFAELQDKVS RCRHALQQMG VGKGDRVVGY LPNIPEAAIA
     FLATASLGAI WAGCAPEFGA QGVIDRFAQI RPKVLFGVTG YTYGDKPVDR SAEFAQIRAG
     LPDLESTVVV PYGQYNSGAA PDSVDWTKLL SEGSEAEMKF EQVDFAHPLC VLFSSGTSGK
     PKAIMHSHGG FVVEHVKNSA LSWDLQAGDR MVWATTTAWM VWNSLLSALL LRASIIMMDG
     NPMYPDLDNQ WRMAEELEPT LMGVSPGFIM ACRHAGIEPG SMYRLDSIRT LGASGSPLPE
     AGHQWVHENF GSDVVFNLGS GGTDVCTAFV QSGPWQRDWA GEMSGKCLGV NVVALDDGGH
     PVEDEFGELV VLDPMPSMPV GFWGDDGDQR YRASYFERYP SAWWHGDRIR FRSDTGSCRI
     SGRSDATLNR GGVRMGTAEF YNVLEERPDV VDSLIVHLEE PAGGHGELVL FVATCDGELT
     TERRASIVTE LRNQLSPRHV PDHIVLVQVI PRNRTGKKLE IPVKKVLTGV PVTDALSLES
     LSAAGAMGPV ERFARQRIAR LTRA
//