ID   A0A1H1EEW8_9ACTN        Unreviewed;       318 AA.
AC   A0A1H1EEW8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=Threonine/homoserine efflux transporter RhtA {ECO:0000313|EMBL:SDQ87371.1};
GN   ORFNames=SAMN05428996_2980 {ECO:0000313|EMBL:SDQ87371.1};
OS   Quadrisphaera sp. DSM 44207.
OC   Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC   Quadrisphaera.
OX   NCBI_TaxID=1881057 {ECO:0000313|EMBL:SDQ87371.1, ECO:0000313|Proteomes:UP000199015};
RN   [1] {ECO:0000313|EMBL:SDQ87371.1, ECO:0000313|Proteomes:UP000199015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44207 {ECO:0000313|EMBL:SDQ87371.1,
RC   ECO:0000313|Proteomes:UP000199015};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNKA01000004; SDQ87371.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1EEW8; -.
DR   STRING; 1881057.SAMN05428996_2980; -.
DR   OrthoDB; 154915at2; -.
DR   Proteomes; UP000199015; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000620; EamA_dom.
DR   PANTHER; PTHR42920; OS03G0707200 PROTEIN-RELATED; 1.
DR   Pfam; PF00892; EamA; 2.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199015};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..318
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011633086"
FT   TRANSMEM        36..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        69..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        279..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          8..142
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
FT   DOMAIN          154..295
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
SQ   SEQUENCE   318 AA;  31993 MW;  B98F754EAFCC2AFE CRC64;
     MLAPRGAGLG LALVSAAAFG TSGALAAVLL DAGWSAGAAV TARVALAALV LTPLALLQLR
     GRRAAPRRGA RAVVVYGLVA VAGCQLCYFN AVARVPVGVA LLLEYSGALL VVAWLWVRHG
     QRPRRLTLGG ALLAVVGLIL VLDLSGDARL DPVGVLWGLG AAVGLAVYFV LAAAAEDPLP
     PLVLVWGGLG TGALALLAAA ATGALAVRAP LTDVVLLGAR VSWLVPVLAL ALVAAALAYV
     AGVRAARSLG ARLAAFVGLT EVLFAVLFAW LLLGQVPASV QLLGGALVLA GVALVRLDEL
     RRREPAPLPG APEAAPTR
//