ID   A0A1H1HG40_9ACTN        Unreviewed;       303 AA.
AC   A0A1H1HG40;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=exopolyphosphatase {ECO:0000256|ARBA:ARBA00012451};
DE            EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN   ORFNames=SAMN04489765_4163 {ECO:0000313|EMBL:SDR24441.1};
OS   Tsukamurella pulmonis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC   Tsukamurella.
OX   NCBI_TaxID=47312 {ECO:0000313|EMBL:SDR24441.1, ECO:0000313|Proteomes:UP000183053};
RN   [1] {ECO:0000313|Proteomes:UP000183053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44142 {ECO:0000313|Proteomes:UP000183053};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC         Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC         ChEBI:CHEBI:43474; EC=3.6.1.11;
CC         Evidence={ECO:0000256|ARBA:ARBA00000209};
CC   -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC       {ECO:0000256|ARBA:ARBA00007125}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FNLF01000002; SDR24441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1HG40; -.
DR   STRING; 47312.SAMN04489765_4163; -.
DR   Proteomes; UP000183053; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   3: Inferred from homology;
FT   DOMAIN          2..289
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
SQ   SEQUENCE   303 AA;  32107 MW;  9E5B7A563ACF1F03 CRC64;
     MVDAHWGAHP TPMSSTKATL RLAEKIEPSG RLSQAGEDAL VESVEEFTKI ARSSGCSEVM
     AFATSAVRDA SNTDTVLAHV KQATGVDVEV LSGVDESRLT ALAVRRWYGW SVGRVLNIDI
     GGGSLELSNG VDEEPDVALS LPLGAGRLTR EWLPDDPPGR RRVGMLRDWL DAEIAPAAAR
     LEAAGTPDLV AGTSKTMRTL ARLTGAAPSS AGPRVKRTLT ASGLRQLIAF ISRMTAADRK
     ELEGLSSDRA GQIVAGALVA EAAMRAMNVE ALDICPWALR EGVILRYLDT QAGFTPENGA
     KSH
//