ID A0A1H1HXM9_9MICC Unreviewed; 556 AA.
AC A0A1H1HXM9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Choline/carnitine/betaine transport {ECO:0000313|EMBL:SDR29888.1};
GN ORFNames=SAMN04489742_4743 {ECO:0000313|EMBL:SDR29888.1};
OS Arthrobacter crystallopoietes.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=37928 {ECO:0000313|EMBL:SDR29888.1, ECO:0000313|Proteomes:UP000181917};
RN [1] {ECO:0000313|EMBL:SDR29888.1, ECO:0000313|Proteomes:UP000181917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20117 {ECO:0000313|EMBL:SDR29888.1,
RC ECO:0000313|Proteomes:UP000181917};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
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DR EMBL; FNKH01000003; SDR29888.1; -; Genomic_DNA.
DR RefSeq; WP_074703527.1; NZ_FNKH01000003.1.
DR AlphaFoldDB; A0A1H1HXM9; -.
DR STRING; 37928.SAMN04489742_4743; -.
DR KEGG; acry:AC20117_23070; -.
DR OrthoDB; 9775735at2; -.
DR Proteomes; UP000181917; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR000060; BCCT_transptr.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000181917};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 521..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 59554 MW; 9BEAD6D9F36CEFFE CRC64;
MKKLQAFSGR GRKGEKEPVL NPGSRAHIDR GPFWICIAFF LAFIIAALID IDSVGAGLNA
ALQWVSMVFG PFFSLLVFAN VLLIGYLVIS RYGSVRLGGD KPEMGFATWV SVMFCSAIAA
GAVFFGPGEP LTHFSDVPPL YSQSVEARSG GAAVVAMQYS FLHWGISAWA IYGTFAIAIM
VAAYHRGLPL RPSSGFYLLL GEKRVRGWWG KVIDIISVLA VVGGVMSSIG LLVIQLSYML
NVQYGVPNNM VVQFSILASC VGVFMLSVVL GVERGIARLS RINVGLALVL GIALLIVGPT
MFILNITVEG FGGYIQDFTK MSLFTDSVDQ SGWLSFWTEY YWAWWLGWGP VVGLFLARIS
RGRTVRQILL GAVSTSSIAL ALWFGILGGT GMSVDISSGG AITKTLDADG MESALLSILN
ELPLSEILIP GFLVVLLLFL ITTADSITLS AAIVSTGVEN PPNSIRIIWG LVIGGTAAVL
LQVGGVSTFQ AAAIVTAPPI AFLLAGAMWS VPKQLNQVRQ LQAPDDKQPT HRDADFGNNS
SAHDDPLRLV SSRPEK
//
