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Database: UniProt
Entry: A0A1H1KDL3_9RHIZ
LinkDB: A0A1H1KDL3_9RHIZ
Original site: A0A1H1KDL3_9RHIZ 
ID   A0A1H1KDL3_9RHIZ        Unreviewed;       516 AA.
AC   A0A1H1KDL3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   16-JAN-2019, entry version 10.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=SAMN05519103_00248 {ECO:0000313|EMBL:SDQ96667.1},
GN   SAMN05519103_06765 {ECO:0000313|EMBL:SDR60316.1};
OS   Rhizobiales bacterium GAS113.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales.
OX   NCBI_TaxID=1884352 {ECO:0000313|EMBL:SDR60316.1, ECO:0000313|Proteomes:UP000199484};
RN   [1] {ECO:0000313|EMBL:SDR60316.1, ECO:0000313|Proteomes:UP000199484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GAS113 {ECO:0000313|EMBL:SDR60316.1,
RC   ECO:0000313|Proteomes:UP000199484};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; FNLG01000001; SDQ96667.1; -; Genomic_DNA.
DR   EMBL; FNLG01000001; SDR60316.1; -; Genomic_DNA.
DR   Proteomes; UP000199484; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000199484};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199484}.
FT   DOMAIN      210    359       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      424    493       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     218    225       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   516 AA;  57165 MW;  ED72972C03576056 CRC64;
     MFENTPQTQS GELLNRASIV TDETVVARAV PGGPALGELW ERVRRKLRAE LGEDVVASWF
     GSLELAGIEG GIAQLSVPTR FLKSWIDTHY ADRLRKHFAI DCNAVSVEVS VRGAMPPRAQ
     TTRIQGRVGD GKAPCEIAAP YLRIDPRSPS DGTLRQDNRQ DKKQEVPMPL SIAAALDRQL
     TFDNFVVGRS NQFACAAARK VAETIGGQAV YNPLYIHAAV GLGKTHLSQA MAHACESEGK
     RALYLTADRF MHQFVSALRS QTAIQFKDQM RNIDLLIVDD VQFLQGKTVQ QEFCHIINQL
     ADSRRQMVVA ADRPPGELEG LDERIKSRLA GGLCVEIAAF DEDLRRRILE RRIAAARERD
     PSFKVPDTVI DFVASVITSN GRDLDGAVNR LLAHASFAGA HVTLDSAETA IRDLIRAREP
     KRVRVEEILK LVSAHFNVTR ADLLSSRRTA SVVRPRQIAM YLSKTLTLRS LPEIGRRFGG
     RDHTTVLHAV RKIEGLIGEN PALKDEVVLL KRMLTD
//
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