ID   A0A1H1KQI0_9ACTO        Unreviewed;       957 AA.
AC   A0A1H1KQI0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Ribonuclease E {ECO:0000313|EMBL:SDR64563.1};
GN   ORFNames=SAMN04489715_0195 {ECO:0000313|EMBL:SDR64563.1};
OS   Schaalia meyeri.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Schaalia.
OX   NCBI_TaxID=52773 {ECO:0000313|EMBL:SDR64563.1, ECO:0000313|Proteomes:UP000181914};
RN   [1] {ECO:0000313|Proteomes:UP000181914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20733 {ECO:0000313|Proteomes:UP000181914};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; FNLK01000005; SDR64563.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1KQI0; -.
DR   STRING; 52773.ADJ76_02285; -.
DR   Proteomes; UP000181914; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd04453; S1_RNase_E; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR   InterPro; IPR004659; RNase_E/G.
DR   InterPro; IPR003029; S1_domain.
DR   NCBIfam; TIGR00757; RNaseEG; 1.
DR   PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR   PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR   Pfam; PF10150; RNase_E_G; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50126; S1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          293..376
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000259|PROSITE:PS50126"
FT   REGION          85..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          669..957
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..127
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..183
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        685..708
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        720..740
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        770..787
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        817..833
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        921..935
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   957 AA;  103765 MW;  5D590E062A155921 CRC64;
     MDVAGVPPWR ESGDDVFNCR RPLRICAPLG FRPSRAMMTG ASGHVARAHH WRIVTTESAN
     PVAPAASLLF QAPVFQAVPE VSTSAAAEEI EPKRRRHSSA SAEANAPREE TAPKRRRRSK
     KSADDADSPD SAAPSSADAG GDEATEQKSR RRRRSKKADE ASAPAADSSD QSDTSSSGSD
     SSDGEESSTR RRRRRARSSA ASASADEGAA ADQVQALKGS TRLEAKKMRR REGRREGRRR
     HSISESEFLA RRESVERTMV IRDQDGLDQI AILEDGLLVE HYVARRTQSS MVGNIYLGRV
     QNVLPSMEAA FVDVGRGRNA VLYAGEVNWD AVGMEGKPRR IESALKSGDP VLVQVTKDPI
     GHKGARLTSQ ITLAGRYLVL IPGGSMMGIS RKLPDKERAR LKKILKAVVP SGSGVIVRTA
     AEGATEGQIR DDVARLTRQW EEIDKKRSAT KAAPVLLRGE PELAVRVVRD IFNEDFTKLV
     IEGRDTYATV KDYVDELSPE LSDRVEQWVG THDVFRAHRI DEQLAKGMDR KVWLPSGGTL
     IIDRTEAMTV IDVNTGKFIG AGGTLEETVT RNNLEAAEEI VRQLRLRDIG GIVIIDFVDM
     VLESNRDLVL RRLVECLGRD RTRHQVTEIT SLGLVQMTRK RVGEGLVEAF SSPCEACEGR
     GFIVHRHPVE TTGGESSSKA SKSSKKQQKK AEPRRVDDSV EHERAKEALS AIAAASSRKE
     EGASDAESTP TKKRRPKGSA AKTQESAAAP AKEPSTTPRG ATETPAAATD EEASTKRPRR
     RRRAAETTPV PELPVHIELP NPVEHAGDPA VPTKDTADIR LPDHQEKAAT TRRRVARKAV
     AASSAEPASA SAPQASRARV ADAEPNIPED GAKAGAFATP DVQPRRTHKR RAAVSTGVVE
     PEASPAPVVV DLPARAEESA PVTPTRSTED ITLPEASGQP RTKRRRRAVS TGIVDAG
//