ID A0A1H1KV57_9BACT Unreviewed; 524 AA.
AC A0A1H1KV57;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05444173_0129 {ECO:0000313|EMBL:SDR65900.1};
OS Opitutus sp. GAS368.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae; Opitutus.
OX NCBI_TaxID=1882749 {ECO:0000313|EMBL:SDR65900.1, ECO:0000313|Proteomes:UP000199432};
RN [1] {ECO:0000313|EMBL:SDR65900.1, ECO:0000313|Proteomes:UP000199432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS368 {ECO:0000313|EMBL:SDR65900.1,
RC ECO:0000313|Proteomes:UP000199432};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LT629735; SDR65900.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1KV57; -.
DR STRING; 1882749.SAMN05444173_0129; -.
DR Proteomes; UP000199432; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:SDR65900.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199432};
KW Transferase {ECO:0000313|EMBL:SDR65900.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 305..517
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 524 AA; 56588 MW; 68FE36675D6992CF CRC64;
MRHSLLFSKV APGTRPSADP HNRPAYWMRR GLSPAREYLE VLAVIVAVTV AGWFTPFSYH
ALGHVYLLTV IMLCLRVGRW PALAAAIVSG LVWNFLFIPP RLSFHVINFD DGLLLGTYFV
VALIAGQLTA FIRTQERFER QREQRATALF HLTRALAGAH TLDEGVTAAL RQADDLFEAQ
TALLLTGENG TLAPHPAGSC SLDQAGLSLA AWTARNRHEA GRFTNVSPEA PVLHLPLLRA
GQVLGVLVVR PPAGATRSTP RQRDLLEAFA AQIALLVERE HLRAAGERAK LLTESDRLHR
TLLDSVSHEL KTPLAVLRAA AENLAKEGGA RRADLPGEIL TATSRLNRVV ANLLSQSRLE
AGAVKPQLDW CDARDLISAA RRGLGDALAG RPFKLEIPAD MPLFMADAPL MEQVVTNLLL
NAVLYTPAGS PLSVSAGVDR QKAQVFLTFA DRGPGIPAAL KAQLFQKFRR GADAQSGGLG
LGLSIVRGLM QAQGGDVTID DQAGPGARFT LRLPCSPHES VPHE
//
