ID A0A1H1LK64_9ACTN Unreviewed; 345 AA.
AC A0A1H1LK64;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:SDR74943.1};
GN ORFNames=SAMN04489717_0390 {ECO:0000313|EMBL:SDR74943.1};
OS Actinopolymorpha singaporensis.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Actinopolymorphaceae; Actinopolymorpha.
OX NCBI_TaxID=117157 {ECO:0000313|EMBL:SDR74943.1, ECO:0000313|Proteomes:UP000198983};
RN [1] {ECO:0000313|EMBL:SDR74943.1, ECO:0000313|Proteomes:UP000198983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22024 {ECO:0000313|EMBL:SDR74943.1,
RC ECO:0000313|Proteomes:UP000198983};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT629732; SDR74943.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1LK64; -.
DR STRING; 117157.SAMN04489717_0390; -.
DR OrthoDB; 9798934at2; -.
DR Proteomes; UP000198983; Chromosome i.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06288; PBP1_sucrose_transcription_regulator; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000198983};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..66
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 345 AA; 36634 MW; 876308B0E7463A4F CRC64;
MPHPSSPEVR AVTIRDVASL AGVSVGTASK ALNGRGKLRQ ETRDRVVEAA RQLGFRPNAL
ARGLLSGRTF TVGLVTSDSF GRFSIPVMLG AEDALGAGQI SVFMCDTRDD PIRERHHVQT
LLARRVDGLL VTGRRTEPRP SIGADLPVPV VYAMTQSTDP GDLSVIPDDE GGGALAVGHL
LATGRSRIAH IAGPSRFLAA RQRAAGVHRA LADAGLPLVG GEPLYGEWTE EWGRQGADIL
LRVEPDVDAI FCGNDQIARG VAETLRERGR RVPDDIALIG FDNWEAMALG SRPPLTTVDM
SLGEVGRIAA EHLLAAIGGR PVTGGVQTIP CRLVVRESTG PRRDA
//
