ID A0A1H1LL07_9MICO Unreviewed; 947 AA.
AC A0A1H1LL07;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Multisubunit sodium/proton antiporter, MrpA subunit /multisubunit sodium/proton antiporter, MrpB subunit {ECO:0000313|EMBL:SDR75216.1};
GN ORFNames=SAMN04489719_0656 {ECO:0000313|EMBL:SDR75216.1};
OS Agrococcus carbonis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Agrococcus.
OX NCBI_TaxID=684552 {ECO:0000313|EMBL:SDR75216.1, ECO:0000313|Proteomes:UP000199649};
RN [1] {ECO:0000313|Proteomes:UP000199649}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22965 {ECO:0000313|Proteomes:UP000199649};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
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DR EMBL; LT629734; SDR75216.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1LL07; -.
DR STRING; 684552.SAMN04489719_0656; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000199649; Chromosome i.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 73..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 794..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 817..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 855..874
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 894..913
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 123..397
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 596..660
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 672..756
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 787..909
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 947 AA; 99047 MW; 847D9485745BF766 CRC64;
MLTVTILAVL GVVASALSGR MGRFVFLLPA AASLAAAVWF GLQGPAMAAG QVLQERVEWM
PALGVAIDLR LGALQWLLAM VVLGVGGLIF VYCAWYFDSK TLASRTVGLL TGFAASMLLL
VLSDDLIVLV VGWELTTVFS YLLVGLNHRS ASNRRAAQTA LIVTTIGGLT MLVGILMLEA
ETSTFSLSAT IADPPRTAAA AWAAALMVVG ALSKSAIVPF QYWLPGAMAA PTPVSAFLHA
AAMVKAGIFL IAAMTPAFVE LPWWRWGLVT LGIATMLLGA VRAMRQLDIK VLLAHGTVSQ
LGLLVTVLGI GTQAAMQAGL TLLAAHAVFK AALFMVVGIV DRTTGTRDLR ELGGLARRMP
VVAGAAILSA ASMAGIPPAL GYLGKEAALD AALGDATGDL TAIGWVAFLG IAVGAALTVA
YSLRLVLGVF FGRLVTEPKR PSGWLVVAPV LLTLLGLVGG FAGETITALL APHASTVPAG
EEAPHLALWH GFTPALVASI LAWIVGALVH RAVGGRRRAP HGQDPLERGY HAGMRALDRL
AVEVTGRTQT GSLPMHLTTI LLVVVAFPGI ALLASGALTG DVRLFDSAGQ VATAVIVSIA
AVITTTTRGR LKAFMLLSVT GYGVALLFLL HGAPDLALTQ ALVETVFLIV LVLVLRRLPK
YFTDRPLRAA RYLRAMLGIA VGTFAAIAAL AAVQARTGEP ISVGFYQQAY EFGHGLNIVN
VTLVDIRAWD TLGEVSVVLA AATGVASLIF VRRPVASVAL LRQPSSGGGR RRWLRGAFTD
ELHSSPVLEM ITRLLFPVMM LVSIFLLAVG HNEPGGGFAG GLVAGIALAV RYLAGGREEL
LEAVPFDAGK LLGGGMAVVV LSVVWPVLIG GRIGESYAIE AVLPLLGEQK LVTTLFFDIG
VWLIVVGAML DFVRSLGAGV DLHGEQNVAP RPQWRSDRSL PGEGVRR
//
