ID A0A1H1MBY7_9ACTN Unreviewed; 932 AA.
AC A0A1H1MBY7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Acyl-CoA synthetase (NDP forming) {ECO:0000313|EMBL:SDR84122.1};
GN ORFNames=SAMN04489717_0755 {ECO:0000313|EMBL:SDR84122.1};
OS Actinopolymorpha singaporensis.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Actinopolymorphaceae; Actinopolymorpha.
OX NCBI_TaxID=117157 {ECO:0000313|EMBL:SDR84122.1, ECO:0000313|Proteomes:UP000198983};
RN [1] {ECO:0000313|EMBL:SDR84122.1, ECO:0000313|Proteomes:UP000198983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22024 {ECO:0000313|EMBL:SDR84122.1,
RC ECO:0000313|Proteomes:UP000198983};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT629732; SDR84122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1MBY7; -.
DR STRING; 117157.SAMN04489717_0755; -.
DR Proteomes; UP000198983; Chromosome i.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198983}.
FT DOMAIN 55..206
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 932 AA; 97625 MW; CC2576D7920ADF01 CRC64;
MEPDRPATKV TPDEGRQDDV LPAEGGQDKV MQDEAGQTVP TTRTVRAVLT DGRVVELRPL
GPGDLDDLLR LHQDLPERDT YLRFFTTHPV GLPELLGPLV QPGDAHRLTV GAFAGQTLIG
AAHYEVLSDP AEAEVAIVVD HRQQAQGLGT LLLEHLASAA RRRGVRRLVA EVLTENAAMV
RVFRDAGLPM TMRLEGSSYL VTLRLVEGAS SYAAAVGERE RLADVASLGA LLRPKAVAVV
GASRRPEAVG HAVLANLLAG GYTGTAHAVN PHADVVAHVR CVPTARDLPA GVDLAVLCVP
AAAVAQAAEE CGERGVRALV VITSGVTDHP ERADALRAAV RKYGMRMVGP NCLGVINTAE
DVRLNATFAR GPAPAGRVGV VTQSGGVGIA LLEQFAAVEL GVSSLVSTGD KFDVSSNDLL
MWWQRDEATD LAVIYVESFG NPRKFGVLAR ALAARKPVLA VRTGTSEVAR RAAASHTAAS
ATPAVNRDAL FEQAGVLAMD SLSEVVATAC VLSWQPLPTG RRVAVIGNVG GIGVLAADAC
ARQGLTLPEL GEVTRAELRS VLPPTASLHN PVDTTADVPD EVFHQCVRAV LEDPGVDAVL
VLTAPTAVTD PLPRLADEVP WELGLPVVAV RVGQTAVVDA LHPTDPATGR PVPVFSDPAH
AAVALGKAVR YGTWRNRPAG TVPDLPNIDV DAARGLVAEF LTAHPDGGWL DPEGVVMLLE
RVGLPMAGVR VARNADEAAM AFAELGGRPV ALKAAAADVL HKSRVGGVLL DLSDEAAVRD
GFGVLHERFG SALTGVVVQP MAAPGRELLV GVSGDPTFGP LVAFGLGGVD TDLVGDRTYR
LVPLTDLDAR EMLTALRAGP ALFGERADPR LDTDGIVDVL LRVGRLAELV PEVAELDLNP
VVATTSSCVV VDARVRLAPA EPGDPFLRRL RT
//
