ID   A0A1H1MXM2_9MICO        Unreviewed;       276 AA.
AC   A0A1H1MXM2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:SDR91377.1};
GN   ORFNames=SAMN04489752_0570 {ECO:0000313|EMBL:SDR91377.1};
OS   Brevibacterium siliguriense.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC   Brevibacterium.
OX   NCBI_TaxID=1136497 {ECO:0000313|EMBL:SDR91377.1, ECO:0000313|Proteomes:UP000199597};
RN   [1] {ECO:0000313|Proteomes:UP000199597}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23676 {ECO:0000313|Proteomes:UP000199597};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629766; SDR91377.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1MXM2; -.
DR   STRING; 1136497.SAMN04489752_0570; -.
DR   OrthoDB; 213853at2; -.
DR   Proteomes; UP000199597; Chromosome i.
DR   GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR   GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR   CDD; cd06578; HemD; 1.
DR   Gene3D; 3.40.50.10090; -; 2.
DR   InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR   InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR   InterPro; IPR039793; UROS/Hem4.
DR   PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR   PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR   Pfam; PF02602; HEM4; 1.
DR   SUPFAM; SSF69618; HemD-like; 1.
PE   4: Predicted;
FT   DOMAIN          27..267
FT                   /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT                   synthase"
FT                   /evidence="ECO:0000259|Pfam:PF02602"
SQ   SEQUENCE   276 AA;  29105 MW;  FE2BD3C551A41C29 CRC64;
     MNQPQTDVGD ELAGRRIVLT AQRRAGQLAS ALERHGAKIV HAPTLSVIPH IDDPELVTRT
     RELIEDRPDI VVVTTGVGFT GWGDVAEAAG LREEWHSMLA GARIFARGPK ARGAIQAAGL
     RVHWVAESET SAEIQQVLLG ECVDGQRIAV QHHGAGADGL DEVFAAAGAD VRSLVIYRWG
     PAPDPAAVVD AVRLVAERRC DAVAFTSAPG AAAFLSAAEE QGLLPAVIEA FNESVVAAAV
     GDVTAAPLHE QGIRTVIPER FRLGALARVL ISELAE
//