ID A0A1H1MZZ1_9BACT Unreviewed; 896 AA.
AC A0A1H1MZZ1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05444173_1339 {ECO:0000313|EMBL:SDR92252.1};
OS Opitutus sp. GAS368.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae; Opitutus.
OX NCBI_TaxID=1882749 {ECO:0000313|EMBL:SDR92252.1, ECO:0000313|Proteomes:UP000199432};
RN [1] {ECO:0000313|EMBL:SDR92252.1, ECO:0000313|Proteomes:UP000199432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS368 {ECO:0000313|EMBL:SDR92252.1,
RC ECO:0000313|Proteomes:UP000199432};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LT629735; SDR92252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1MZZ1; -.
DR STRING; 1882749.SAMN05444173_1339; -.
DR Proteomes; UP000199432; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000199432};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 268..338
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 342..394
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 532..757
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 778..894
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 829
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 896 AA; 98300 MW; A91BB5CC87413C79 CRC64;
MSGWFTQNTD YLVFLVLVAS LWLGLGLWLH RTGRLASLPK ITWLLLAVVA GGGWWAVNRA
GYDAQGNIRR QVELLVPYYV QEMQQAGHAR LADNPPPGDA LYEKLIQMEI NWLKLNPAIA
DVYTFRRRAD GAIFLLADSE TDYDHNGRIA SARGQRTPPG EIYEGLTPAL NRAFRGELIF
DEDIVEDRRG RWVSVFAPLR NASGLVEAVL GVDFDATQWL EQRTRARLMT LWFLGGAILL
FTGPALLVTV LRHDLQRRRQ VEVQLREQAE VRRIIFDHAP GGIALADLNN RLLEVNDALC
TMLGYRRDEL LQLSFVQITH PDDVGKNLTL NRQITSGEIR VGQLEKRYIR KDGSVIHAAL
SVGLARDEQG APRFFVGQVT DITERRQVES ELHLRQKQLA AILAHAPIIL FATDLQGIYT
LCEGAALTAI GYQPGAAVGQ SIFDRYAARP DILGDIRRAL AGESLAIQRE INGVIFEGRC
MPQREADGRI TGMIGITIDV TDRVAAARER EKIEHKLLEV QKLESLGVLA GGVAHDFNNL
LTAIMGNTSL ARQSLPPGSP LTGNLDQVEQ ASQLAAGLCQ QLLAYAGRSR LDPQITDLNT
LVRETTDLLR LSIGNHAQLR LNLAPDLPGL MADPAQIRQV LLNIVQNAAE AIGRRDGVIT
LTTRVLAVDA AWLAEASSGR ELPPAAYVCL EVTDNGPGLD RAARSRVFDP FFSTKGSGRG
LGLAAALGIM RSHKGALRLV SEPGQGATFT LAFPPNARPA PKSVASAPSA PTWRSSGTVL
IVDDEQAVRA TAAQMIAFFG FTVKQAESGQ QALDFLRQRG SRFDLVLLDL TMPGMDGYAT
FTALRQLQPD QRIVVFSGYS AQDAQQRFAG QNLNGFLQKP FSTDSLRDVL REATLN
//
