ID A0A1H1QEN8_9CELL Unreviewed; 517 AA.
AC A0A1H1QEN8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN04489860_1064 {ECO:0000313|EMBL:SDS21895.1};
OS Paraoerskovia marina.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC Paraoerskovia.
OX NCBI_TaxID=545619 {ECO:0000313|EMBL:SDS21895.1, ECO:0000313|Proteomes:UP000185663};
RN [1] {ECO:0000313|EMBL:SDS21895.1, ECO:0000313|Proteomes:UP000185663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22126 {ECO:0000313|EMBL:SDS21895.1,
RC ECO:0000313|Proteomes:UP000185663};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; LT629776; SDS21895.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1QEN8; -.
DR STRING; 545619.SAMN04489860_1064; -.
DR eggNOG; COG3525; Bacteria.
DR Proteomes; UP000185663; Chromosome i.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06568; GH20_SpHex_like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 2.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000185663}.
FT DOMAIN 3..161
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 165..331
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 338..481
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 57..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 328
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 517 AA; 55584 MW; 950041C1A4A72865 CRC64;
MFSLIPQPLS LQAGDGAPFA LAGAVIRGGA TEPEQRLARR AAQTLTRAAG VAVSTGSTSV
SAGSTSVSAG STSVSAGSTS VSAGSTSVSA GSTIELRLDP ALATDRPTSD DRYVVEVTAD
GIVARAAAVP GLHLAVATIA QLVRPASGET PAHVPAVVVE DEPRYAWRGL SVDIARNFFG
PESLQRVLDL ASSYKLNRLH LHLTDDQGWR IDTPSRPLLT DISSKTAMNG NPGGFLTLDE
YEELQVYAED RGIVIVPEID VPGHVNAATH AYGELMPDGR ATDAYEGMEV GFSKLSIDLP
ATEPFLRDVF GDLAAATHGD YLHIGGDEVK QMQDGEFGRF VDLLERVVLD TGKKVAAWHE
AAHAQVRPET LVQFWDTNHV QLEPLQRAAA NGTRFIMSPG NHVYLDMKYT ADYALGQDWA
GLVELSDAYV WNPDEAVEGI SGDSIVGVEA AVWTETLTTL DELNDMLMPR LPAVAEVAWT
PQDAKDWDGF RERLVRHVPG WERDGVAFHR TPQVTWE
//
