ID A0A1H1S0G5_9SPHI Unreviewed; 530 AA.
AC A0A1H1S0G5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=HDIG domain-containing protein {ECO:0000313|EMBL:SDS41306.1};
GN ORFNames=SAMN05216490_1109 {ECO:0000313|EMBL:SDS41306.1};
OS Mucilaginibacter mallensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=652787 {ECO:0000313|EMBL:SDS41306.1, ECO:0000313|Proteomes:UP000199679};
RN [1] {ECO:0000313|EMBL:SDS41306.1, ECO:0000313|Proteomes:UP000199679}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP1X4 {ECO:0000313|EMBL:SDS41306.1,
RC ECO:0000313|Proteomes:UP000199679};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|RuleBase:RU003953}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT629740; SDS41306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1S0G5; -.
DR STRING; 652787.SAMN05216490_1109; -.
DR Proteomes; UP000199679; Chromosome i.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR GO; GO:0042245; P:RNA repair; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 1.10.246.80; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR47545; MULTIFUNCTIONAL CCA PROTEIN; 1.
DR PANTHER; PTHR47545:SF1; MULTIFUNCTIONAL CCA PROTEIN; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000199679};
KW RNA repair {ECO:0000256|ARBA:ARBA00022800};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 85..211
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 238..297
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
FT DOMAIN 315..432
FT /note="HD"
FT /evidence="ECO:0000259|Pfam:PF01966"
SQ SEQUENCE 530 AA; 60428 MW; 8EF8900E663545B8 CRC64;
MLSASRSMSV KACPYASTST QHDTDFLDIK TTLPPLPIAE ERVKTIITNE RQNNLLILPH
YMKQHLQHSI FNTISKIAGE HNLQAYVIGG FVRDIFLNRP SKDTDIVVIG NGIDFAEKVA
KKLNVKLAVF KNFGTAQLKY QDLEVEFVGA RKESYRLDSR KPIVENGTLE DDQKRRDFTI
NALAISLHPD TFGELLDPFE GMADLEQKLI RTPLNPVETF SDDPLRMMRA IRFASQLNFR
IDDIAVTAIK SNTDRISIVS QERITDELNK IILSPKPSIG FNYLFDTGLL HKIFPQMVAL
YGVDYIDGRG HKDNFYHTLQ VLDNICETTD DLWLRWAAIL HDIAKPATKR FEQGHGWTFH
GHEDRGARMV PKIFAQLKLP LNEKMKLVQK LVQLHLRPIV LSQSIVTDSA VRRLLFEAGD
DIEGLMLLCK ADITTKNEYK VKKYRQNFDL VIQKLKDVEE RDNIRNWQPP ITGTDIMQLF
GIKEGREVGI IKNQIREAIL EGEIPNEREA AIAYTILKGE EIGLKVVATL
//
