ID   A0A1H1S9Q5_9ACTN        Unreviewed;       190 AA.
AC   A0A1H1S9Q5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Thiol-disulfide isomerase or thioredoxin {ECO:0000313|EMBL:SDS44850.1};
GN   ORFNames=SAMN04489812_1937 {ECO:0000313|EMBL:SDS44850.1};
OS   Microlunatus soli.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Microlunatus.
OX   NCBI_TaxID=630515 {ECO:0000313|EMBL:SDS44850.1, ECO:0000313|Proteomes:UP000199103};
RN   [1] {ECO:0000313|EMBL:SDS44850.1, ECO:0000313|Proteomes:UP000199103}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21800 {ECO:0000313|EMBL:SDS44850.1,
RC   ECO:0000313|Proteomes:UP000199103};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629772; SDS44850.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1S9Q5; -.
DR   STRING; 630515.SAMN04489812_1937; -.
DR   Proteomes; UP000199103; Chromosome i.
DR   GO; GO:0016209; F:antioxidant activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd02966; TlpA_like_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR000866; AhpC/TSA.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR42852; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   PANTHER; PTHR42852:SF6; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   Pfam; PF00578; AhpC-TSA; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:SDS44850.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199103};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..190
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009259799"
FT   DOMAIN          45..188
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REGION          46..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   190 AA;  19732 MW;  1EF02BE866261DD9 CRC64;
     MAVVAVLLIL VGLAGCSTNS AGQNSQTGSE NGYVAGDNQL TRVPVKDRKQ APVISGPSVA
     DTDKTISSAD HAGTVIVVNV WGSWCGPCRK EAPDLQEASA ETAGTAQFIG IDSRDSGVAQ
     PRAFQRANKI DYPSIYDPDG SQVVKFENLP PSAIPSTMVI DKQGRVAVRI LGPISKATLV
     DIISDVAAGK
//