ID   A0A1H1STS3_9FLAO        Unreviewed;       377 AA.
AC   A0A1H1STS3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Membrane fusion protein, multidrug efflux system {ECO:0000313|EMBL:SDS51253.1};
GN   ORFNames=SAMN05216503_3299 {ECO:0000313|EMBL:SDS51253.1};
OS   Polaribacter sp. KT25b.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=1855336 {ECO:0000313|EMBL:SDS51253.1, ECO:0000313|Proteomes:UP000199117};
RN   [1] {ECO:0000313|Proteomes:UP000199117}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KT25b {ECO:0000313|Proteomes:UP000199117};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; LT629752; SDS51253.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1STS3; -.
DR   STRING; 1855336.SAMN05216503_3299; -.
DR   OrthoDB; 9801814at2; -.
DR   Proteomes; UP000199117; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR   PANTHER; PTHR30158:SF23; MULTIDRUG RESISTANCE PROTEIN MEXA; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   PRINTS; PR01490; RTXTOXIND.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199117};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..377
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009260402"
FT   DOMAIN          65..275
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
SQ   SEQUENCE   377 AA;  40771 MW;  0716593775C83DF3 CRC64;
     MKHHKLLTLV TLSIFLVAVS CTNNEKQKTA AVQGLAPSFP VVNLQTKTVT GFTDYPATIE
     GIVNSDVRAK TSGYIEKVYV DEGAKVRKGQ ALFKLETQSL SQDADAAKAL VNVAQVEVNK
     LIPLVEKNII SPVQLETAKA NLEQAKANYS SVSANIGYAT IKSPIDGYVG AINFREGALI
     SPSDATPLTT VSEIDQVYAF FSFNEAQYID HLQRSEGQNK AERIKNSPDL TLILANGKEY
     SEKGRIQTST GQINQSTGTI TIRAAFNNPN EILTNGNSGK IRFPIEYKDA IVVPQTATFE
     QQGNIMIFKL SADNKIATSI IKVKGTVGNL YVVESGVDVK DQIVVSGVGK LRNGMAISPQ
     VTPFDEAIKP IATLFKN
//