ID A0A1H1T6W2_9MICO Unreviewed; 427 AA.
AC A0A1H1T6W2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MFS transporter, YNFM family, putative membrane transport protein {ECO:0000313|EMBL:SDS55928.1};
GN ORFNames=SAMN04489751_2292 {ECO:0000313|EMBL:SDS55928.1};
OS Brevibacterium sandarakinum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=629680 {ECO:0000313|EMBL:SDS55928.1, ECO:0000313|Proteomes:UP000199700};
RN [1] {ECO:0000313|EMBL:SDS55928.1, ECO:0000313|Proteomes:UP000199700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22082 {ECO:0000313|EMBL:SDS55928.1,
RC ECO:0000313|Proteomes:UP000199700};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; LT629739; SDS55928.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1T6W2; -.
DR STRING; 629680.SAMN04489751_2292; -.
DR OrthoDB; 63984at2; -.
DR Proteomes; UP000199700; Chromosome i.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17324; MFS_NepI_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43271; BLL2771 PROTEIN; 1.
DR PANTHER; PTHR43271:SF1; INNER MEMBRANE TRANSPORT PROTEIN YNFM; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..422
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 214..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 44225 MW; 01E13276EDA6A15B CRC64;
MSTGEPSATS TRRTIIAVFL AGVSVFLVLY ETQGLLPAIR GAYGIDAPTA SLTVSATNVA
MAVFLIPFSL LAPRIGHARQ IAGGVVLAAL LALILPFMPS PELLIAVRFL QGVAIAAVPA
TAMAYLSLRL PAAALPGAIG VYIAGNTIGG LSSRLLTGLA AEVLGWHGGL AFTAALSLVF
GLIVVWLLRH DLFSTSRALA ARDGVATARD DSITAQDAST AGRDASAAAG PGQPPRRAII
PLGSGLWRIY LTGFLCMIVF GGSFTMLGTR LQHDPWHLSE GAVALFFLIY LVGTVVTTYY
GRLATKYSRT SLTLLGMITA LAGAGLTLVD SLVVIIIGMS LLTGGFFLGH TGASAAASAS
RPGVDSTRSA AIYLTVYYLG TSLGAWLSAV LFTDYAWPGV VVMCMTALFA VLILTLTGAS
IGFKKRN
//
