ID A0A1H1TTK4_9FLAO Unreviewed; 928 AA.
AC A0A1H1TTK4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN04487764_2661 {ECO:0000313|EMBL:SDS62939.1};
OS Gillisia sp. Hel1_33_143.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Gillisia.
OX NCBI_TaxID=1336796 {ECO:0000313|EMBL:SDS62939.1, ECO:0000313|Proteomes:UP000199552};
RN [1] {ECO:0000313|EMBL:SDS62939.1, ECO:0000313|Proteomes:UP000199552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hel1_33_143 {ECO:0000313|EMBL:SDS62939.1,
RC ECO:0000313|Proteomes:UP000199552};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; LT629737; SDS62939.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1TTK4; -.
DR STRING; 1336796.SAMN04487764_2661; -.
DR Proteomes; UP000199552; Chromosome i.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199552};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 592..925
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 928 AA; 103769 MW; 4A659B737981022C CRC64;
MTIDIASVDP KQNIIIKGAK LHNLKNIDVV IPRNKLVVIT GLSGSGKSSL AFDTLYAEGQ
RRYVESLSSY ARQFLGRLNK PKVDYIKGIA PAIAIEQKVN STNPRSTVGT STEIYDYLKL
LFARIGRTYS PISGDEVKKD TVTDVINYVK AFAEGEKLLL LAPLLLEEGR EIEDKLKVLL
QQGYSRIKIK NEVVRIDEAV TDKVKLDDIY LVVDRIVTKE EEDFYNRLAD ASQTAFFEGK
GELFIESISD NKIRHFSNKF ELDGIHFLEP NVHLFSFNNP YGACPKCEGY GDVVGIDEDL
VIPNTGLSVY ENAIFPWRGE SMSWYKNELI NNSHKFDFPI HKPYFDLSQD QKDLIWNGNE
YFEGLNTFFE FLESKAYKIQ NRVMLSRYRG KTKCSLCKGK RLRKEANYVK IGGATITDLV
EKPLDKVRAF FNDLELNEYD AQIAKRLLAE IKNRLQFLSN VGLDYLTINR KSNTLSGGES
QRINLATSLG SSLVGSMYIL DEPSIGLHPR DTKKLIGVLE DLRDLGNTVI VVEHDEDIMK
AADEIIDIGP EAGTHGGELV ASGTYADILK SDSLTAQYLN DSMRIEVPKK RRTTKQFAKI
LGARENNLKN IDVTFPLGVF TAVTGVSGSG KSTLVKKILY PSMLKEIGGI GEKAGQFSAI
EGNFKSITSI EFVDQNPIGR SSRSNPVTYI KAYDDIRNLF ANQKLSDIRN FKPKHFSFNV
DGGRCDTCKG EGEVTIEMQF MADVHLECET CNGKRFKKEV LEVTFAEKNI DDILKMTIDE
ALGFFSENNE NKITNKLRPL QEVGLGYVQL GQSSSTLSGG EAQRIKLASF LVKGITKDKA
LFIFDEPTTG LHFHDIQKLL TSFNALIDKG HSIIVIEHNM DLVKCADHVI DLGLDGGENG
GYLIAAGTPE EVAKNKKSYT APYLKEKL
//
