ID A0A1H1UCF2_9MICO Unreviewed; 790 AA.
AC A0A1H1UCF2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN04489752_2299 {ECO:0000313|EMBL:SDS70103.1};
OS Brevibacterium siliguriense.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=1136497 {ECO:0000313|EMBL:SDS70103.1, ECO:0000313|Proteomes:UP000199597};
RN [1] {ECO:0000313|Proteomes:UP000199597}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23676 {ECO:0000313|Proteomes:UP000199597};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; LT629766; SDS70103.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1UCF2; -.
DR STRING; 1136497.SAMN04489752_2299; -.
DR Proteomes; UP000199597; Chromosome i.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152:SF2; DRUG RESISTANCE ABC TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 471..776
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 790 AA; 83957 MW; A44842B0DDEF2BB3 CRC64;
MHTADSHDLI HVSGARENNL KNVSVEIPKR RLTVFTGVSG SGKSSLVFHT IAAESQRMIN
ETYSAFVQGF MPAMARPEVD VLEGLTTAIL VDQERIGANP RSTVGTVSDI NAKLRTLFAR
LAEPNLGSTN AYSFNVATLS GKGAVTIDKG EGKQVERKSF SVNGGMCPHC EGMGTATDIS
IAEVVDESKS LNDGAITVPG YKPGGWSVRM FSESGYFDPD RPIADFDETE RHYLLYAQGE
KVRINGTNIT FDGLVPRIQR SFLSKDRDSM QKHIREFVDR AVVFTTCPEC EGTRLNAAAR
SSQIAGKSIA DVCALQISDI TDWLDRIEPG AASGLLDSLR ADVKAFNDIG LGYLSLDRSA
GSLSGGEAQR IKLVRHLGSS LTDVTYVFDE PTIGLHPHDI RSMNELLLAL RDKGNTVLVV
EHKPETILIA DHIVDLGPGA GSNGGEVTFT GTVAGLRESD TLTGRHLGYT AALKDAVREP
EGALEIRDAQ SHNLRDVDVD VPLGVLTVVT GVAGSGKSSL IEGSLRGRDG VVMIDQAPIK
GSRRSNPATY MGMLEPIRKA FAKANGVKPA LFSANSEGAC PVCNGAGIIY SDIALMGGVS
APCDECEGKG FQAEVLEFTL GGRNIREVLD LPVDAAIEYF GAGESRIPAV IKVLKMLAEV
GLGYVSLGQP LTTLSGGERQ RLKLAVHLST KAADAAKVII LDEPTTGLHL ADVENLLRLL
DRLVDSGRTV IVVEHHQAVM AHADHIIDLG PGAGHDGGSI VFEGTPAELV SGAKTIGSLT
AKHLAAYVNS
//
