ID   A0A1H1VDE1_9ACTN        Unreviewed;       627 AA.
AC   A0A1H1VDE1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SDS82209.1};
GN   ORFNames=SAMN04489716_1708 {ECO:0000313|EMBL:SDS82209.1};
OS   Actinoplanes derwentensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=113562 {ECO:0000313|EMBL:SDS82209.1, ECO:0000313|Proteomes:UP000198688};
RN   [1] {ECO:0000313|EMBL:SDS82209.1, ECO:0000313|Proteomes:UP000198688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43941 {ECO:0000313|EMBL:SDS82209.1,
RC   ECO:0000313|Proteomes:UP000198688};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT629758; SDS82209.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1VDE1; -.
DR   STRING; 113562.SAMN04489716_1708; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000198688; Chromosome i.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000198688}.
FT   DOMAIN          165..502
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         186..193
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   627 AA;  68757 MW;  78F85B5841C7628C CRC64;
     MLSLELLYLQ RVRDALAWML DHARMRVTTG EQIAGDRYTA ETLGRMLKSH AKELASEPDG
     PPYFGRMDYD DHRYYIGRRR ITDATGAALV IDWRAPVSAR FYQAGARNPL GVTARRRYGW
     TMTVPAQLTG FEDEDLLREY AEPSRLLTEE IERPRVGPMR DIVATIQPDQ DELVRTALNR
     SLCIQGGPGT GKTAVGLHRA AYLLYTHREQ LKRTGVLIVG PNPAFLRHIA AVLPALGEID
     IRQRTLSDLL GTPQLADDPA ADTVKHDPRM AAVLAAAIRA TISAPIGDLV VPDGSVRLRV
     PEADLARLAG RIRAENLPHE LGRERLRARI TGLLARQIES RGESTGYAWT QRISRCKPVK
     AVLDQVWPKV RPDDLLATLL SDPATLARAA DGILTAAEQA TIRRPRRSRR WSAADLVLLD
     EIAGLIDHPE SFGHIVVDEA QDLSPMECRV IARRNRHGSL TVLGDLAQGT SGWAAADWPA
     QMAHLGRPDA PITALTRGFR VPAVVLNYAN RLLPALGVSV PATTSVRADG SLTVDEIPDV
     ATAVRAALTY EGSIAVIATE SRLATINPDI IDVRVTLLPA HLAKGLEFDH VIVVNPQEII
     DAEPRGQNRL YVALTRAVSR LDVLSVL
//