ID A0A1H1VN43_9ACTN Unreviewed; 388 AA.
AC A0A1H1VN43;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Regulator of protease activity HflC, stomatin/prohibitin superfamily {ECO:0000313|EMBL:SDS86153.1};
GN ORFNames=SAMN04489717_4137 {ECO:0000313|EMBL:SDS86153.1};
OS Actinopolymorpha singaporensis.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Actinopolymorphaceae; Actinopolymorpha.
OX NCBI_TaxID=117157 {ECO:0000313|EMBL:SDS86153.1, ECO:0000313|Proteomes:UP000198983};
RN [1] {ECO:0000313|EMBL:SDS86153.1, ECO:0000313|Proteomes:UP000198983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22024 {ECO:0000313|EMBL:SDS86153.1,
RC ECO:0000313|Proteomes:UP000198983};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the band 7/mec-2 family.
CC {ECO:0000256|ARBA:ARBA00008164}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT629732; SDS86153.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1VN43; -.
DR STRING; 117157.SAMN04489717_4137; -.
DR OrthoDB; 9809197at2; -.
DR Proteomes; UP000198983; Chromosome i.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08829; SPFH_paraslipin; 1.
DR Gene3D; 3.30.479.30; Band 7 domain; 1.
DR InterPro; IPR001107; Band_7.
DR InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR InterPro; IPR018080; Band_7/stomatin-like_CS.
DR InterPro; IPR001972; Stomatin_HflK_fam.
DR PANTHER; PTHR43327:SF63; PROTEIN QMCA; 1.
DR PANTHER; PTHR43327; STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL; 1.
DR Pfam; PF01145; Band_7; 1.
DR PRINTS; PR00721; STOMATIN.
DR SMART; SM00244; PHB; 1.
DR SUPFAM; SSF117892; Band 7/SPFH domain; 1.
DR PROSITE; PS01270; BAND_7; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:SDS86153.1};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Protease {ECO:0000313|EMBL:SDS86153.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198983};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 20..178
FT /note="Band 7"
FT /evidence="ECO:0000259|SMART:SM00244"
FT REGION 300..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 42100 MW; 243CC5A1E692F51A CRC64;
MAPLIFFLVL AILVVVVLAR SVRIIPQARA GIVERLGRFA RTLGPGLSII VPFVDKVRYT
IDLREQVVSF PPQPVITEDN LVVSIDTVIY FQVTDPVAAT YEIANYIQAI EQLTMTTLRN
IVGGMDLERT LTSREQINTE LRGVLDEATG KWGVRVNRVE LKGIDPPPSI QDSMEKQMRA
DRDKRAAVLT AEGVRQSAIL TAEGEKQSAI LTAEGEKQSQ ILRAQAQRES QILRAQGEAQ
AIETVFNAIH EGEPDQRLLS YQYLQMLPKI AQGDANKLWI VPSEIGKALE GIGSMVGKFA
EEGETPPARP ADGIRRRTPR PEVTAAAVEA EEATDTALQD AESEVQAAIA AAEDAAKGGL
GGRRQQETGT NGDSAGPAQP AAQEPRPE
//
