ID   A0A1H1WNC5_9ACTN        Unreviewed;       300 AA.
AC   A0A1H1WNC5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=B12 binding domain-containing protein {ECO:0000313|EMBL:SDS98522.1};
GN   ORFNames=SAMN04488543_2777 {ECO:0000313|EMBL:SDS98522.1};
OS   Friedmanniella luteola.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Friedmanniella.
OX   NCBI_TaxID=546871 {ECO:0000313|EMBL:SDS98522.1, ECO:0000313|Proteomes:UP000199092};
RN   [1] {ECO:0000313|EMBL:SDS98522.1, ECO:0000313|Proteomes:UP000199092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21741 {ECO:0000313|EMBL:SDS98522.1,
RC   ECO:0000313|Proteomes:UP000199092};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629749; SDS98522.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1WNC5; -.
DR   STRING; 546871.SAMN04488543_2777; -.
DR   OrthoDB; 9800334at2; -.
DR   Proteomes; UP000199092; Chromosome i.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 1.10.1660.10; -; 1.
DR   Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR   Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR   InterPro; IPR003759; Cbl-bd_cap.
DR   InterPro; IPR036724; Cobalamin-bd_sf.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   InterPro; IPR047057; MerR_fam.
DR   InterPro; IPR036594; Meth_synthase_dom.
DR   PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR   Pfam; PF02607; B12-binding_2; 1.
DR   Pfam; PF13411; MerR_1; 1.
DR   SMART; SM00422; HTH_MERR; 1.
DR   SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR   SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR   PROSITE; PS50937; HTH_MERR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199092}.
FT   DOMAIN          22..91
FT                   /note="HTH merR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50937"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   300 AA;  31836 MW;  C8BCDC7D46C2CF54 CRC64;
     MQNESPLHRD DPSGETASTG RTLSIGEVGL LLGLPAPTIR SWERRHGLST TARDERGHRR
     YTDNDVAVLR RMRDQRSTGM AVGAAAAVAQ APSSLELCGQ MLAGTHHLDG DEISAVLDVS
     LRAHGLAATL EEVLLPAMRE VGVQWSRGHC DVANEHLATA AVLAWLARRA PDAPPPLPGR
     PIVLSGGPQD QHTIGLEAFA VLLRHHRFDC RNLGAQTPAA SLRFAVERSS AAGVVVASQL
     ARNRPAAVAA LKAVSDTEAV LFYAGAAFRS ARSRQSLPGH HLRGSLSHAA DLISSHLGRA
//