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Database: UniProt
Entry: A0A1H1WQU9_9ACTN
LinkDB: A0A1H1WQU9_9ACTN
Original site: A0A1H1WQU9_9ACTN 
ID   A0A1H1WQU9_9ACTN        Unreviewed;      1865 AA.
AC   A0A1H1WQU9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   11-DEC-2019, entry version 12.
DE   RecName: Full=DNA primase {ECO:0000256|SAAS:SAAS00993443};
DE            EC=2.7.7.- {ECO:0000256|SAAS:SAAS00993444};
GN   ORFNames=SAMN04488543_2804 {ECO:0000313|EMBL:SDS99627.1};
OS   Friedmanniella luteola.
OC   Bacteria; Actinobacteria; Propionibacteriales; Nocardioidaceae;
OC   Friedmanniella.
OX   NCBI_TaxID=546871 {ECO:0000313|EMBL:SDS99627.1, ECO:0000313|Proteomes:UP000199092};
RN   [1] {ECO:0000313|EMBL:SDS99627.1, ECO:0000313|Proteomes:UP000199092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21741 {ECO:0000313|EMBL:SDS99627.1,
RC   ECO:0000313|Proteomes:UP000199092};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629749; SDS99627.1; -; Genomic_DNA.
DR   BioCyc; GCF_900105065:BLT72_RS13975-MONOMER; -.
DR   Proteomes; UP000199092; Chromosome i.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd03364; TOPRIM_DnaG_primases; 1.
DR   Gene3D; 3.90.980.10; -; 1.
DR   InterPro; IPR013264; DNA_primase_core_N.
DR   InterPro; IPR037068; DNA_primase_core_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR034151; TOPRIM_DnaG_bac.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR014862; TrwC.
DR   Pfam; PF08275; Toprim_N; 1.
DR   Pfam; PF08751; TrwC; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|SAAS:SAAS00993445};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199092};
KW   Transferase {ECO:0000256|SAAS:SAAS00993442}.
FT   DOMAIN          1604..1687
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|PROSITE:PS50880"
FT   REGION          1169..1188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1355..1414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1790..1865
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1356..1375
FT                   /note="Pro-rich"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1790..1811
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1825..1849
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1850..1865
FT                   /note="Pro-rich"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1865 AA;  199827 MW;  4E0A45BDC6D8DA0A CRC64;
     MSIHKLTAGS GYDYLTRQVA ALDATDKGHT GLAQYYSQRG EQPGVWVGAG MAGIDGLAVG
     DPVTAEQMQA LFGHGLHPLA DQNRERLAGP DLTEADYRAV TRLGAPFRIY SPDVSPFRRE
     VAARIAAVNK TAGLPGDWPV PLPERARVRT EVATEFFRRE HGRNPAGPRE LAGTIAELSR
     PQTTAVAGFD LTFSPVKSVS TLWAVADRPV AALVEEAHRA AVADALRFLE SHALFTREGT
     NGVRQVNVRG LVAAAFTHRD SRAGDPDLHT HVAVANKVQT LDGRWLAVDG RILFKATVVA
     SETYNTALEH HLTTLVGVRF AERPNSDPRK RPVREIVGVD PTLNNRWSAR RQAIESRQAE
     LAAAFQHAQG RPPTSVEAVQ LAQRATLETR DNKHEPRSLA DQRATWRAQA LQVLGGPRQL
     HGMLTNTLNP PSRPSVQTDA EWVERTARAV VATVEGQRAT WQVWHLRAEA HRRLRSTDTA
     GPEIERLVDR IVQHSLTGSV RVDRPGDGVV EPRELRRVDG ASVYTVAGSA LYTSYRILAA
     EQRLVAIAGH TDHRRLDPAL VEQAIAASTA DGVALDDGQA GLVRAMASSG CRLQLAIAPA
     GAGKTTALAA LTRAWTADGG QVVGLAPSAA AAGQLRGHTG APTDTLAKLT WAIDHHTDLP
     DWATRIGPRT LVLVDEAGMA DTLSLDTAVA FVTGRGGSVR LVGDDQQLAA IGAGGVLRDI
     ATTHGAIRLH QLHRFTDPAE AAASLALRDG RPEALGFYLD QHRVHVGDQT TMTDQVFTAW
     QTDRSKGLDA VMLAPTRDLV ADLNSRARTH RLATTQDTPP TREVVLADGN QASAGDLVLT
     RSNDRRLRVT ATDWVKNGDR WTVLNLPPTG GLTVQHTQTH RTVTLPRDYV QTAVELGYAT
     TVHAAQGVTA DTTHGLADGR ESRQQLYTML TRGRTANHLY LPVVGDGDPH TVIRPGTTHP
     LTPTDMLEQI LARDAAPLSA TTLRRVDSEP MSRLGDACDR YRDALHVAAE HLAGPDTLTA
     LHHIAETLSP GLTDEPAWPT LQAHLLLHAA DGDNLTELLT AVAGQRELGS ALDRAAVLDD
     RLDDRPLRTP GPLPWLPGIP DQLAAHPQWG NYLTRRAALV TQLADQVRIS TEPDRTTPGI
     TTPSWAEQQP GRLAPELVLA VQVWRAATHV DPDDRRPTGP RGQDRVGRAW QDELNRRLAG
     DTPAVKEWAP LLTQLHPSLA GDPFTGVLAG RLAALNRTGT PAVQLLRQAA AGSALPDDHA
     AAALWWRITR HLTPATKAPA YPQSSEGWAE RLAGHVGATR AAGLQCSPWW PALSNTIDRG
     LHRGWTLHDL LPPQRLGTGL PGEPEALTLL RRATTLTTPP PPPTEENPPT PQDLPPADLW
     DGFDAASGHR LPGSASTTDT RRPDAPAEPA AATSNADYLD ADLAVAAMVR DTLGPLPPSA
     ADHERAYQRA LAWDHSPVTR ERLVAVNDLA CQFYQSQLPG SWGQAYLTER LRTDLTGHPD
     YRPGHAPAAW TALTTHLRRH GVTDDELTAA GLVTIASTGQ LIDRFRDRAL LPITADGEVL
     GFVGRRHPDR DNAGPKYLNT PTTPLFHKGD QLYGALDQPL HDGAVPVLVE GPLDAIAVTL
     ATNSRCIGVA PLGTALTHEQ AAQLATYGAD PVVATDNDAA GRTAAGRAYW LLTAHNLDPG
     HAQLPANSDP AQLLAERGPT ALGSALLRAQ PLGDTMINVR LAHLTGSEAA AELAQIIAAR
     PAQEWEPAVR SAAARSGLPV DHLSRQLLSA ARARNVDPLA ASEAALQTLR HSSARPAASN
     GQDQRQVGAK LSAPTGASAR PSAARFRAAN STRNRASSGS GTRTTRMPAP RPGTQPPPPP
     TMGRV
//
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