ID   A0A1H1XJ38_9ACTN        Unreviewed;       384 AA.
AC   A0A1H1XJ38;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=S-adenosylmethionine:tRNA ribosyltransferase-isomerase {ECO:0000313|EMBL:SDT08839.1};
GN   ORFNames=SAMN04489717_4987 {ECO:0000313|EMBL:SDT08839.1};
OS   Actinopolymorpha singaporensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Actinopolymorphaceae; Actinopolymorpha.
OX   NCBI_TaxID=117157 {ECO:0000313|EMBL:SDT08839.1, ECO:0000313|Proteomes:UP000198983};
RN   [1] {ECO:0000313|EMBL:SDT08839.1, ECO:0000313|Proteomes:UP000198983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22024 {ECO:0000313|EMBL:SDT08839.1,
RC   ECO:0000313|Proteomes:UP000198983};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629732; SDT08839.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H1XJ38; -.
DR   STRING; 117157.SAMN04489717_4987; -.
DR   OrthoDB; 9783887at2; -.
DR   Proteomes; UP000198983; Chromosome i.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008616; P:queuosine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1780.10; QueA-like; 2.
DR   InterPro; IPR003699; QueA.
DR   InterPro; IPR042118; QueA_dom1.
DR   InterPro; IPR036100; QueA_sf.
DR   PANTHER; PTHR30307; S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE; 1.
DR   PANTHER; PTHR30307:SF0; S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE; 1.
DR   Pfam; PF02547; Queuosine_synth; 1.
DR   SUPFAM; SSF111337; QueA-like; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Isomerase {ECO:0000313|EMBL:SDT08839.1};
KW   Queuosine biosynthesis {ECO:0000256|ARBA:ARBA00022785};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198983};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDT08839.1}.
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          92..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          139..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  40754 MW;  7729BC738E7A1E01 CRC64;
     MSAGTTTAVQ AAGTAPNVLP APRVDFVLPP ELEAHEPPEA RGLTRDGVRL LLGRGDGSGD
     GPANEVAHHR FVDLPHLLEP GDVVVVNRSG TRPAAVDLPT HPEDTDSTDS TDSTGTTGEG
     ERRSVHFSTL AADGSWLVEL RRGDGPDPGG RPGRRIDLPG GASLVLRERH RSGRLWHAVP
     IVPPAVPDVP AYLARYGRPI RYGYVGRDWP LHAYQTAFAT TPGSAEMPSA GRPFTPEVVT
     ELVARGILVV PITLHTGVAS AEFHEPPYAE WFEVPAATAA VVNDANERGA RVVAVGTTVV
     RALESAAHGS WVRAASGWTE LVVTAERGVA VVSGLLTGFH EPQASHLLML EAIAGPELVR
     RCYAAAVEEG YLWHEFGDVN LLLP
//