ID A0A1H1YQL9_9ACTN Unreviewed; 3719 AA.
AC A0A1H1YQL9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RHS repeat-associated core domain-containing protein {ECO:0000313|EMBL:SDT23632.1};
GN ORFNames=SAMN04489716_2952 {ECO:0000313|EMBL:SDT23632.1};
OS Actinoplanes derwentensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=113562 {ECO:0000313|EMBL:SDT23632.1, ECO:0000313|Proteomes:UP000198688};
RN [1] {ECO:0000313|EMBL:SDT23632.1, ECO:0000313|Proteomes:UP000198688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43941 {ECO:0000313|EMBL:SDT23632.1,
RC ECO:0000313|Proteomes:UP000198688};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LT629758; SDT23632.1; -; Genomic_DNA.
DR STRING; 113562.SAMN04489716_2952; -.
DR OrthoDB; 4981820at2; -.
DR Proteomes; UP000198688; Chromosome i.
DR CDD; cd00081; Hint; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR InterPro; IPR045351; DUF6531.
DR InterPro; IPR044927; Endonuclea_NS_2.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR031325; RHS_repeat.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR InterPro; IPR006530; YD.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 9.
DR PANTHER; PTHR32305; -; 1.
DR PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR Pfam; PF20148; DUF6531; 1.
DR Pfam; PF13930; Endonuclea_NS_2; 1.
DR Pfam; PF13385; Laminin_G_3; 3.
DR Pfam; PF07591; PT-HINT; 1.
DR Pfam; PF05593; RHS_repeat; 7.
DR Pfam; PF00652; Ricin_B_lectin; 1.
DR SMART; SM00306; HintN; 1.
DR SMART; SM00560; LamGL; 2.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198688};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 3533..3559
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
FT REGION 72..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2343..2362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3270..3375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3460..3488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2345..2360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3288..3348
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3719 AA; 394964 MW; E4B44F8BA8C2618B CRC64;
MFLRILSLDL GGTVGRHARR LAVFLVLTLV ASMGIPSGLK GDLPLGWLDF RLSWTQAAAA
YVSLPVQKQG PGADGHYGGK KAGFTQPEPV KRKPWTADEA VGADSFDPAD SKKVTGRSSS
TTDVFENPDG SQTAKVSTGR VNYRGADGKW RPIDTSLSRG TDGRLKTKAN SFGVSLAAPQ
AKSAARQAAE DLARITLPTG EVFAYRLQDA LAVTPAVDGD KSTYAEILPG VDVRLQTLTN
SVKETIVLKS PAATREFVFP LELTGLTADL TADGGLALRD AANEVVLTVP RPFMEDSSPL
DGTGSRPKSY AIGYSLIDVD GTPALKVTAD DAWIDDPKRV WPIEIDPTVY TAKTMNEGDV
YVDNDTTTGA DEQNGSSIAV GRYENVIARS YMKFQDFDTD GFVGKRITGA KLWAYLTYAY
TCDVYSNIYV RKVTTPWLVG DLDTAALAAG PSVTAPIGTL KITDHTPGCT NTVKDRSVGQ
WHAVTLDPTT LHDWATNRGS ANWDQGLAIT GDEVATNSWK RFTSGNYSDA YKAYLEVTYA
NNVAPQVNTL FPPSGTQSPS LTPQLIADGY DPDGFPATLE YNFEVFQESA TGTQTKIKES
GWRTDKTWTV PAGTLKWGGR YRWQVTLNDG RNNEGVASYT WSPSWRFLLT TPVPQSPLTA
SLEQHGDAGF APGSGTYTSS AVDAQVSSVG PALEIARTYN SVDTRLSGAF GAGWSSLVDA
KVTERKDATG ALTVAEVTYP TGQTVAYGRN ADGTWSAGLG RYAKFAAVTG GYQLTDKSGV
GYLFTSATGT TGVYGLTSVT DTNGRPLNLT WTGGKVTQVT SAASKRNLFL TWSGAHVASV
VTDPAVAGDA ATAATWSYTY SGDQLAKVCP PTSATACTQY TYTDGNLYPT TVENLDAYSY
WRLGEASGVA QAASAATERM KADYGTHTNV TLGTAGSGAL PGSTATAATY NGTTSRTALP
AKTVSQAGYQ SVSMWFKTSA AGDHVLYSQS WDPITTASTA NPYQPVLYVG TNGQLYGSFP
TLPAAGTTLG SFLGSASGRC LDAENDGLSN GSNVILQDCT GAGKQIWKLT AAGQLHQNGL
ATRCMREEGT EAGSGVDVQD CSATAANQKW RLTGDGRIVS QESGMCVNPY GNGTVNGTVM
TIWPCGRPYT AVQTFSTQNH STLASATAVN DGNWHHAVLS AAGDRQTLYV DGVAKATQTG
VVVTDIQPRY QYLGAGHLGG TWTAQDNAVA YKNNGSPDYY SGALSDVAVF DQPLTADRVT
ELYGARASRK LLSQITRPSG AVTAKVAYDP VSGRVRKVTD GDNGSWTLAD PQVKGSSQVY
ASAVLGDNPV DYWRLNDLPG TTEPYNEVNG NTATYSSVTL GGTPGTDGPF KDTTAPLFSG
VAGSEITGDT ASVSTAQSFS VSTWLNAADL TVNRAAVAIT GAAQSTAFML SYDKATNKWA
AVMCSADVTG STCPRTASTS TPVANTWTHL AATFDAPTKT MRLYVNGVLE KTAVLTHTLW
AGSTLVAGHC FHNAVNCDLW KGRVAEIATY QARLTDAEIL AQFNSADRSA TGVAMPAKSI
AVTGPTAKNS TQLFNLYTGQ QIADTDTLGN LTQFGYDGTT GAMTLKVDPN GNKTELAYDV
RGNVLSQTTW PDQTDTATRS TTRFTYFPDA TSTNPAPDPR NDKILTVQDG RTDGTYRTTY
TYDTRGNTTA VTDPLGRVTT TVHSDGTTGA PAGLATRQVS PGGSVTTTEF AANGDITAVT
DPAGKITRLT YDQLGRVLTS TEVSKTNPNG LTSGYTYDKL GRILTLTQPG VLNRVTGATH
TAVTTYQYNV DGQSTAISVT DTTGGDTARQ TTTEYNTLGQ VKRETEPDGT ATAYTYDLFG
EVLTATDDAG TTVATEYDSE GQILSVRFKN YTGDPDDPKA AADVVTESRA YDPGGRLIRS
TDAEGWSTEY AYTSNNLLKT ATQIGATAAT RFVLEDNTYD LAGNLLKQVT NDGRTTTAYT
IDAAARPYQV TVDPTGVNRK VTNVLSPDDL VLASTVRDSA GTVVAQNETI YDPAGNDLVN
TTFSGSTNGP AGRWKLGETT GTVGADTAGN TPAEFPSWAA TQWSTDKPAS RTDLTGSVQM
TEADTYEQLT TPVPVVDAAR SYSVSAWVKL KNPTQNHAAV SQESGQSSAF VLGYTHDSKS
WWMAVCDNGG VNCTSAESTQ TAATDAWTHL TGVYDAAAKT VKLYVNGTLQ NTVAWCCAAN
TVNGTFAIGG SKWDGWLTAE WAGNLADVQA YQRVLSDADV TAVYDGSSTW AGAKLIRESF
ERDTDGTITS ELDPNGERTY YQYDEAGRMA LTIDPPTTTE RYDSAPVTTR SISYAGYNTF
GELTEERDPT GNTTTTRYDA GGRPVKTIYP SYTAKGSATA LWPEETTQYD AVTGEVSKVI
DAAGNETSLT YDALGRVTKV TNADGGLVRY TYDRLGNVLS VTDPTGAKQT STYDYLGRTE
TETQIVRQTG AAHTSTYTYG PGGWLSQATS PDKATEKYTY NALGETLTST DSANATTTYQ
YGGAGDLLRT TLADNTYQTT TYDLASRPTA AQSYDAAGTL LTSTGVTYDR ASNVVAATDA
RGATTKFTYD AAGLLTAQDE PVVAGTTSIG TSFGYDAAGR PTRFTDGRGN AFWTTYNTWG
LPESTIEPAT TAHPAEADRT FTTVYDLAGL PVRQIQPGGV EVVNTYDEMG QVTRSSGSGA
EAQTTDREYA YDLAGRVTEL SGPGGDNTLA WDDRSLLTSV TGPSGNSSFT YTGDGQTKTR
VDAAGTTTYG YDPAGRLSTI ANPSTGIQET VGYDALSQVT KVTYGTNGNT RNLGYDSLHR
LTTDELKTTA GASVARISYG YDQNSNLTSK TTTGFAGATA NSYTYDLANR LTSWNNGTTT
VGYEYDRSGN RTRAGTKTFT YDDRNRLLTS SQGDSYEYTA RGTLRRTLSG TVGYETTADA
FGQIIRQQSG DNTFENYQYD GLGRVVKTGF AYTGLENDLA TDGTSTYTRD PGGGLLGVQG
LYAWTDRHTD LVAQFTATGA SLSGSTTYDP LGNVVTRAGV IGNLGFQQEY TEQSTGRVNM
HARWYNPETG QFDTRDTAGL SPVGNSGNAN RYGYGNANPL SNIDPTGHWS MSISGCNTTW
TCLVQGFVNS FDVIGMASSV IDAFGDLSGT INRFIGGMVT DANNWKTTIS NVIHDKFDCG
AWWVPMREST CNNIVSKVAT VGGWACALSG VCQIIYDCLN YNSGGKNGCA EAVGGLLADA
VKALVTVGAG AVVSRVANRI TSLLKRFGLP DRRKKSSSGS GNSGTKKPKK ASKPKSEKKK
TKAKTKKKSS NSTKKSTKKK KSSNSTKKTK SKKKNTKAKT KTPKKTTTKP KGTGKTPVKS
TPVKETAPEP RLELPTARVL DGNDIGYDNR TDYGTCPGHS FDPVTRVLMA DGTTKPIAEV
ELGDEVKTTD PETGETTSQP VTVLHHNLDT ELADVTVSDT PSNVTAETGE GKGGRSTRGP
TVLKTTGNHP FWDDTAKQWV GAGDLEPGKS TLLTADGATV HVTAVRTFTG AKRMLDLTVD
VIHTYYVLAG TEPVLVHNCL TQDSYDFGGQ VRYGALDKYD RPTGVWATVT KDMLHKGQSP
GGLKIEGLPK GMGTLLNLAR GHLLADRLGG KRNKKNLVAL TQDPVNSPIM RDGIEQTVYD
AVDGGQVVQY SIEPVYVGKS DTPRALRISA YGNGPNPLVV KEFELNNPAG MFGFGDEDW
//
