ID A0A1H1ZV69_9MICO Unreviewed; 770 AA.
AC A0A1H1ZV69;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04489721_3347 {ECO:0000313|EMBL:SDT37146.1};
OS Agromyces flavus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Agromyces.
OX NCBI_TaxID=589382 {ECO:0000313|EMBL:SDT37146.1, ECO:0000313|Proteomes:UP000199482};
RN [1] {ECO:0000313|Proteomes:UP000199482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPCC 202695 {ECO:0000313|Proteomes:UP000199482};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; LT629755; SDT37146.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H1ZV69; -.
DR STRING; 589382.SAMN04489721_3347; -.
DR OrthoDB; 9757990at2; -.
DR Proteomes; UP000199482; Chromosome i.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 391..609
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 627..740
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 747..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 676
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 770 AA; 84349 MW; C9701FE416B6D0B3 CRC64;
MVGERDHPVD EERFRRLERD YNDATEQFVA MNEVLTALGR SSSDPDAVLD TVVESARRLC
RCEAAQVYLI DGDQFVLSSS VGLSDEFVRY VDEHPFQRDR RTLIGRVTLD RKVQQIADVL
SDPEYGRQDV QEIARYRTLV SAPMLLDDDV VGALSLWRSE VDPFDARAIA LLEAFAAQAA
IVVRNAHLVR ELEQRSAELA RRVEQLEALS DVGAVVSSSL VLDEVLQNII MNAVRFSGCD
GGSIMEYVEE ERCFSVRSAY ASSAELLRKL RGIRVELETT LVGRAALEGH PIAVADLDTV
EHLDPHLKLL HDDGWRSVLA VPVLRGDRII GALVVRRKRP GAFSEETVEF LETFASQSAL
AVWNAQLFRE LETKTAELQV VSQHKSEFLA SMSHELRTPL NAVIGFSEVL LERMFGELNE
RQDEYLRDIL SSGRHLLQLL NDILDLSKVE AGRMELSTSR FSVRSVMEYG ISMVRERAGL
HGIAVTLEVD PAVDGIESDE LRIKQVLVNL LSNAVKFTPD GGHVDVVARR DGDELAVTVT
DDGPGIAPDD RERIFESFQQ GRRGPQREEG TGLGLTLCRR IVTLLGGRMW LESELGAGST
FGFSVPMHRP APSSPVAQDG DGHHLPVIVV VDDDRASLDL MTAYLDGLGV RVVLGRDGNE
GIELIRAHAP AAVILDIRLP GMDGWSVLTT LRDDEATRDI PVVIVSILDE RSRGLAHGAA
DYLVKPVGRD DLVGALRRVG AVGASGTGVD ASTGPAADLP ASTPPGRGAS
//
