ID A0A1H2BLQ7_9ACTN Unreviewed; 435 AA.
AC A0A1H2BLQ7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Cysteine synthase {ECO:0000313|EMBL:SDT59118.1};
GN ORFNames=SAMN04489716_4717 {ECO:0000313|EMBL:SDT59118.1};
OS Actinoplanes derwentensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=113562 {ECO:0000313|EMBL:SDT59118.1, ECO:0000313|Proteomes:UP000198688};
RN [1] {ECO:0000313|EMBL:SDT59118.1, ECO:0000313|Proteomes:UP000198688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43941 {ECO:0000313|EMBL:SDT59118.1,
RC ECO:0000313|Proteomes:UP000198688};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; LT629758; SDT59118.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2BLQ7; -.
DR STRING; 113562.SAMN04489716_4717; -.
DR OrthoDB; 9805733at2; -.
DR Proteomes; UP000198688; Chromosome i.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProt.
DR CDD; cd01561; CBS_like; 1.
DR CDD; cd00158; RHOD; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000198688}.
FT DOMAIN 343..434
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 435 AA; 46992 MW; BEE9C1BB6819E81C CRC64;
MRFDDITESI GNTPLVRIEP AVHGLANIDL YAKLELLNPF GSVKDRAAWN MVRPLLPGAA
ERGDTVVELS SGNTAKALAM IAGMHGLKFR SVTNRMRVPE IKDLLLLLGA EIDELPGRSE
CLDPSDTEDP LTRMYQRLDT DGGGYVHTDQ YFNPLNVDAH VNGTGAEIVK DLDGNAPDFF
IACVGTAGSS TGVARALRQQ NPDTRVIGLV AAKNDFIPGI RTIDEVHEVG LFEPSVYDVI
EPVSADEAID GLLALVRRCG ILAGPTGGGA FQGALHFLRT IDASLPSRKS AVFIVCDRVE
SYLSYLRDRR PALFGRPPRP NTIASLGDIS DFPAVSVLDA PAFTRDALVI DVRNPYAYQA
LHIDGSINIA DEVFADMLQA GLPFSRRRPV LLVCPVGERS AAYAALLTRM GHPDARSLDG
GIIAWRDAGL ELVRD
//
