ID   A0A1H2CJX5_9ACTN        Unreviewed;       247 AA.
AC   A0A1H2CJX5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Type-5 uracil-DNA glycosylase {ECO:0000256|ARBA:ARBA00023887};
GN   ORFNames=SAMN04489716_5978 {ECO:0000313|EMBL:SDT70557.1};
OS   Actinoplanes derwentensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=113562 {ECO:0000313|EMBL:SDT70557.1, ECO:0000313|Proteomes:UP000198688};
RN   [1] {ECO:0000313|EMBL:SDT70557.1, ECO:0000313|Proteomes:UP000198688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43941 {ECO:0000313|EMBL:SDT70557.1,
RC   ECO:0000313|Proteomes:UP000198688};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the uracil-DNA glycosylase (UDG) superfamily.
CC       Type 5 (UDGb) family. {ECO:0000256|ARBA:ARBA00023779}.
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DR   EMBL; LT629758; SDT70557.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2CJX5; -.
DR   STRING; 113562.SAMN04489716_5978; -.
DR   OrthoDB; 9787663at2; -.
DR   Proteomes; UP000198688; Chromosome i.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0033958; F:DNA-deoxyinosine glycosylase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004844; F:uracil DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd10031; UDG-F5_TTUDGB_like; 1.
DR   Gene3D; 3.40.470.10; Uracil-DNA glycosylase-like domain; 1.
DR   InterPro; IPR044147; UdgB-like.
DR   InterPro; IPR005122; Uracil-DNA_glycosylase-like.
DR   InterPro; IPR036895; Uracil-DNA_glycosylase-like_sf.
DR   PANTHER; PTHR33693; TYPE-5 URACIL-DNA GLYCOSYLASE; 1.
DR   PANTHER; PTHR33693:SF3; TYPE-5 URACIL-DNA GLYCOSYLASE; 1.
DR   Pfam; PF03167; UDG; 1.
DR   SMART; SM00986; UDG; 1.
DR   SMART; SM00987; UreE_C; 1.
DR   SUPFAM; SSF52141; Uracil-DNA glycosylase-like; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198688}.
FT   DOMAIN          63..237
FT                   /note="Uracil-DNA glycosylase-like"
FT                   /evidence="ECO:0000259|SMART:SM00986"
SQ   SEQUENCE   247 AA;  26359 MW;  FB77895060858C1B CRC64;
     MLSSARTPPA VEEQAAATAS LSLLDARIAD CFACPRLVTW RNDIAVTKRA AFRDQEYWGR
     PVPGFGPGGA EIAILGLAPA AHGGNRTGRL FTGDRSGDVL FAALHRAGLA NQPTSVAADD
     GLELRHTRIF AAVRCAPPDN KPLPAERDTC APWFRRELQL IRPTLKVVVA LGAFAWAAWW
     PAMTAAYGAR PPVPRPKFGH GALVEVPGAP VLLGSFHVSQ QNTFTGRLTP LMLDEVFGRA
     KVLAGLA
//