ID A0A1H2DA20_9ACTN Unreviewed; 452 AA.
AC A0A1H2DA20;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN04489716_8846 {ECO:0000313|EMBL:SDT79580.1};
OS Actinoplanes derwentensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=113562 {ECO:0000313|EMBL:SDT79580.1, ECO:0000313|Proteomes:UP000198688};
RN [1] {ECO:0000313|EMBL:SDT79580.1, ECO:0000313|Proteomes:UP000198688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43941 {ECO:0000313|EMBL:SDT79580.1,
RC ECO:0000313|Proteomes:UP000198688};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; LT629758; SDT79580.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2DA20; -.
DR STRING; 113562.SAMN04489716_8846; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000198688; Chromosome i.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000198688}.
FT DOMAIN 16..66
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 69..388
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 242
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 452 AA; 49287 MW; 7058EC8224A19D32 CRC64;
MTPGPVPPGA EVRTRVDPTL AAEGYVLSCG PAGIDLAGGS EAGVFYGRQT LRQLGPDVPG
VHIEDAPRFT WRGVMLDVAR HFMPVPDVLR FVDLIAFHKL NVLHLHLTDD QGWRIEVPGW
PRLTTVGAWR SSTMLGSRVH DLHDGEPHGG FYTTADLRQI VEYAARRHVT VVPEVDMPGH
MQAAVAAYPA LGNGFDGPVR TGWGISSHVL NLSEATFDFC RRVLDHVCDI FPSEFIGIGG
DECPTVEWPG GRELQADFTA RMASHLATRG RRVYGWDEIL AGGAPDGAVI AAWRGVEPAD
VAIRAGHQVV CCPDVKLYLD YRQSDDPGEP TPVGTLLTLE DVYTYEPPSS PLVLGAQANI
WTEHMESRSR VEYMAFPRLC ALAEVVWGPA ERDFGDFTAR LPAHLARLGA LGVNYRPLSG
PRPADARPSA PGNPRTLADR LAELHEMTAD LR
//
