ID   A0A1H2DCV3_9ACTN        Unreviewed;      1450 AA.
AC   A0A1H2DCV3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family {ECO:0000313|EMBL:SDT80419.1};
GN   ORFNames=SAMN04489716_9195 {ECO:0000313|EMBL:SDT80419.1};
OS   Actinoplanes derwentensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=113562 {ECO:0000313|EMBL:SDT80419.1, ECO:0000313|Proteomes:UP000198688};
RN   [1] {ECO:0000313|EMBL:SDT80419.1, ECO:0000313|Proteomes:UP000198688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43941 {ECO:0000313|EMBL:SDT80419.1,
RC   ECO:0000313|Proteomes:UP000198688};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629758; SDT80419.1; -; Genomic_DNA.
DR   STRING; 113562.SAMN04489716_9195; -.
DR   OrthoDB; 9807790at2; -.
DR   Proteomes; UP000198688; Chromosome i.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR   PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 2.
DR   SMART; SM00382; AAA; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR   PROSITE; PS50901; FTSK; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00289};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000198688}.
FT   DOMAIN          623..815
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   DOMAIN          963..1157
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   BINDING         641..648
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT   BINDING         980..987
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ   SEQUENCE   1450 AA;  154166 MW;  4DD26D6B9B01FE8B CRC64;
     MRLNVSLVSE DSPTAEPLVV EAEPGTSVRA FAAELAEAVG GSPGTLFHGA TPLDPRMSLA
     EARLGAGAEL GLNRPARSSA GRSGAVEVRL VSGPGAGGIV LLPPGEYEIG GAATCRVRLP
     GEVPPVAARL LVTVDRTVEV TAVSATEMDG VTLEGTTEWP AGRQLAIGGI LLELATGVPA
     RAPLTRAADG FTWEFNRPPR FFPQIPGGKF RLPAEPVKPE KNHFPLVTLL LTPAIGALVG
     ILATGNWRFI FLALVSPIGA LLTQFSSKRR GTQSFAEQMQ EHDEKLARVR ADIDEAVLEE
     QRARRYAYPD PAFTGRIATL PGERLWERRR HDDDFLALRV GTCSMPSTVR VEDPALDEHR
     RVTVPELGQV PVAVDVRAAG VVGVAGSRLT RLAPWLVSQA AVLHSPDDLI ICVLTDAGAE
     NRWSWVRWLP HARADGEEAY VRIGTTAESV SRRIAELNRM IAARSAADRQ NPAERGAASG
     EPDILVVFDG ARRLRSMPGA ITLLRDGPAA GVHVLCLEPE ERLLPEECRA VVVSDDTGAS
     VRTATTAQVT GIRADEPDAG WYERAARRMA SLGASGDGDE TVLPQSARLL DILDLEPPTP
     DKIAAGWVVR PRSTEAVLGA GMDGRFAIDL VRDGPHALIA GTTGAGKSEL LQTLVATLAV
     ANRPDEMTFV LVDYKGGSAF AECEQLPHTV GMVTDLDTHL VERALTSLGA ELRRREHVLA
     AAGASDIIRY QERRARDTSM PPMPRLVLVI DEFASMVREL PDFVTGLVNI AQRGRSLGIH
     LVLATQRPSG AVTPDIRANT NLRIALRTTD QGESRDIIDA PDAGELSPRT PGRAYARLGY
     AALLPFQAGR IGGKRPVRGD RADEVRIEIT HVDWSRLGDP VPARRGSGTP AGGPADTDLK
     ELVAAVVAAT ERLGVPRQPS PWLQPLAEVV QWAELPQPAG SVRPGDLGAV AYGIVDLPAS
     QSREALMFDV DRTGHIFFVG SGRSGRSQAL RTLAAALAAR HSSADVHLYA VDCGNGALLP
     LAGLPHCGAV VDRLQTERLD RMLTWLNSEL TRRQALFGEQ GVADLAEQRR NAPADQRLPH
     IVLLMDRFEV FERDFATYDN GSYLDRLTRV LRDGAGVGVH VVLAGDKVLG SGRFAGATEE
     KLILRLNDRS DYSLLGLNLR EVPPELGPGR ALRMADHAEA QIAVLGPDIS GQGQAAALVE
     GARQITARDA GVPSHARPRR FAALPELIGY AEMRRMLPTE GKPLTATVGV GGDDMVPLGP
     DFADIPTFAI GGPPRSGRST ALLSVARTLL ANGTGLIVIA PRRSPLRDLA GQPGVTAVVT
     DAGVAAVDFR KLLKSIPEET GTVVIDDAEL LAQSDIDGDL NTLARGAAGN GWGLAVAGNA
     EALSLGLAGW LTQLKRNRAG LLIAPQSITD GDLIGMRIPR GIVGQTAQPG RAYLHLGDGT
     LTAVQVPKAE
//