ID   A0A1H2EJB9_9FLAO        Unreviewed;       643 AA.
AC   A0A1H2EJB9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Heparinase II/III N-terminus {ECO:0000313|EMBL:SDT95246.1};
GN   ORFNames=SAMN04487762_0860 {ECO:0000313|EMBL:SDT95246.1};
OS   Polaribacter sp. Hel1_33_78.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=1336804 {ECO:0000313|EMBL:SDT95246.1, ECO:0000313|Proteomes:UP000198843};
RN   [1] {ECO:0000313|EMBL:SDT95246.1, ECO:0000313|Proteomes:UP000198843}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hel1_33_78 {ECO:0000313|EMBL:SDT95246.1,
RC   ECO:0000313|Proteomes:UP000198843};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
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DR   EMBL; LT629794; SDT95246.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2EJB9; -.
DR   STRING; 1336804.SAMN04487762_0860; -.
DR   OrthoDB; 7335480at2; -.
DR   Proteomes; UP000198843; Chromosome i.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.70; -; 1.
DR   Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR   InterPro; IPR008929; Chondroitin_lyas.
DR   InterPro; IPR012480; Hepar_II_III.
DR   InterPro; IPR031680; Hepar_II_III_N.
DR   PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR   PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR   Pfam; PF07940; Hepar_II_III; 1.
DR   Pfam; PF16889; Hepar_II_III_N; 1.
DR   SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198843};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          76..327
FT                   /note="Heparin-sulfate lyase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16889"
SQ   SEQUENCE   643 AA;  75653 MW;  F0AA8DC449C8D052 CRC64;
     MLKWYFFRLK TMSLLEIPYR FKQILQKKFE SFFVVGETLG TILIPKTKKI LKIGEIDTPI
     FDDEFSVFGK KINFFDSQID WHKDVFSGEK YALTFSKNIN IRKSANLSAK NVWEINRLQF
     LIHIAINYNK TKDEKFLDKF IELNESWIEA NPYLLGVNWY SNIEVNIRLI NWFFCWELLD
     AEELMNKSKI FKEFVNTKWL PVIYQHCKYS FNNPSKYSSA NNHLVSEYSG LYLATSVWGF
     KESEFWRSYA KDGLEKEILK QHSNGVNKEE AAEYIQFITD FFLLPFIIGE KCNDSFSKEF
     QKALKQILDY ILVFTDVNLN FPKYGDEDDG YVLNFSEIGH FNNFKSLLVS ASIIFNDESY
     LSAKSEYDIK NKLLFSDDGY LLFEKLMDRE KKELVTKFYP KEGHFIFRKL IKDKEIYAHL
     DIAPLGYLSI AAHGHSDILS FLIHVNGNPF FIDSGTYSYH TEKKWRKYFV SSQAHNTITI
     DDENQAFHAS DTLWLNHYKP KVISCVQQRN IERVVGTYNQ KSNVQHIRSF EFNKKINEFL
     IEDNIIIRDN KEHKIFMPFH LHPTIQITKS TITNYTLSHA SGAAVSLHLD DQLKWNLVRG
     SAEPFLGWYS ESFMKKEPTS VVFGEMIVKE SLKIVTRIKV TEY
//