ID A0A1H2EVW6_9BACT Unreviewed; 780 AA.
AC A0A1H2EVW6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Cu+-exporting ATPase {ECO:0000313|EMBL:SDT99282.1};
GN ORFNames=SAMN05444156_1308 {ECO:0000313|EMBL:SDT99282.1};
OS Verrucomicrobium sp. GAS474.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Verrucomicrobiaceae; Verrucomicrobium.
OX NCBI_TaxID=1882831 {ECO:0000313|EMBL:SDT99282.1, ECO:0000313|Proteomes:UP000198591};
RN [1] {ECO:0000313|EMBL:SDT99282.1, ECO:0000313|Proteomes:UP000198591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS474 {ECO:0000313|EMBL:SDT99282.1,
RC ECO:0000313|Proteomes:UP000198591};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
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DR EMBL; LT629781; SDT99282.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2EVW6; -.
DR STRING; 1882831.SAMN05444156_1308; -.
DR OrthoDB; 199028at2; -.
DR Proteomes; UP000198591; Chromosome i.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF5; CATION-TRANSPORTING P-TYPE ATPASE-RELATED; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00943; CUATPASE.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Cell membrane {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000198591};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 120..138
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 212..234
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 378..397
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 409..433
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 724..743
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 1..91
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 780 AA; 82537 MW; 011913F4424B71EF CRC64;
METILDVEGM TCSGCARNVR EALAGVEGVE LAEVDLEGKN AVVTWAEQPE APVVGRGGEI
EGRAKARRKA EERERAALLV RAVKQAGYGA KPRREREPGE PGRVDLEPAE RTGSLWSAPL
FFLGIPVTVT LMVAEWGFDA NNGNAGGGYG WLAFALALPV QIGLGFPFYR NAWRQLFRNR
LTMDTLVSLG STAAFGLSLY ELVGFVAGGS TGHLHVSFLE SSSILTLVGA GHWLEGRLAT
RSGAALRALL RSVPQSVLRF PGRGGAGGPG EAVEVPLASL AKGDLVLVKP GDRIPIDGEI
VEGYGAIDES LLTGESLPAE KGPGFPVRAG TFNTDGRLVV RVDGLGSETA LAGIVRAVER
AQSSRAEIER LVDRVSRYFV LVVITLAILT FFGWGFLSAI GWEASLLRAV AVLVVACPCA
MGLATPAALM AAANAASRRG ILFRDASAIE KTGKIDTVLF DKTGTLTGEL TVKAVEFPPR
AKGEAPVLPP SLFPSLVRAL AAPSHHPLCR ALVHHYPKAA PLAVEGWREE RGAGVVGRCE
GRTARLGSPA WLIASGVVFP DAFLPRLGGG PLALAIGEEV AALITFVKPV RREAAAVIRG
LEKDGYAVYM VTGDEESPAL AVAQEVGIKG TRVYFGIRPE EKADLVVRMR AVGEGRKEKR
VAFVGDGIND GPALAAADLG IAVLGASDVA REASDMVLLT RDLEAVPEAL RLSAATLRVI
RENLFWAFFY NAAMVPLAMI GMVPAVACAL AMGLSDLCVM GNAMRLLRYG RKVRVKEVRS
//
