ID   A0A1H2HC26_9PSED        Unreviewed;       713 AA.
AC   A0A1H2HC26;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=SAMN05216580_2240 {ECO:0000313|EMBL:SDU29289.1};
OS   Pseudomonas guangdongensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1245526 {ECO:0000313|EMBL:SDU29289.1, ECO:0000313|Proteomes:UP000243063};
RN   [1] {ECO:0000313|Proteomes:UP000243063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCTCC 2012022 {ECO:0000313|Proteomes:UP000243063};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC       {ECO:0000256|ARBA:ARBA00005446}.
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DR   EMBL; LT629780; SDU29289.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2HC26; -.
DR   STRING; 1245526.SAMN05216580_2240; -.
DR   OrthoDB; 9760034at2; -.
DR   Proteomes; UP000243063; Chromosome i.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:InterPro.
DR   CDD; cd17920; DEXHc_RecQ; 1.
DR   CDD; cd18794; SF2_C_RecQ; 1.
DR   Gene3D; 1.10.150.80; HRDC domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010997; HRDC-like_sf.
DR   InterPro; IPR002121; HRDC_dom.
DR   InterPro; IPR044876; HRDC_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032284; RecQ_Zn-bd.
DR   InterPro; IPR018982; RQC_domain.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR01389; recQ; 1.
DR   NCBIfam; TIGR00614; recQ_fam; 1.
DR   PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR   PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00570; HRDC; 1.
DR   Pfam; PF16124; RecQ_Zn_bind; 1.
DR   Pfam; PF09382; RQC; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00341; HRDC; 1.
DR   SMART; SM00956; RQC; 1.
DR   SUPFAM; SSF47819; HRDC-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50967; HRDC; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SDU29289.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243063}.
FT   DOMAIN          26..194
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          215..364
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   DOMAIN          527..607
FT                   /note="HRDC"
FT                   /evidence="ECO:0000259|PROSITE:PS50967"
FT   REGION          506..527
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   713 AA;  79365 MW;  B9B0B327D0A62B7E CRC64;
     MLDSAQRILK DVFGYDAFRG NQARIIQRVG AGGDALVLMP TGGGKSLCFQ VPALLREGVA
     VVVSPLIALM DDQVATLDEL GVAAVALNST QTPDEQREIA ERLRRGEIKL LYLAPERLVQ
     PRMLAFLQRL KIALFAIDEA HCVSQWGHDF RPEYLQLGQL AELFPQVPRI ALTATADMRT
     REEIAQRLHL QEAERFLSSF DRPNIFYRIV PKDQPRKQLL GFLEGRRGDA GIVYCMSRKK
     VEELASFLAE QGYPALPYHA GLPNEVRAHN QRRFLNEEGL IMVATIAFGM GIDKPNVRFV
     AHLDLPKSLE AYYQETGRAG RDGLPSEVWM AYGLQDVLFL RQMLQSSEGD ERHKRVERHK
     LEAMLALCEE TRCRRQALLA YFDEELPQPC GHCDNCVDGV ETWDATEAAR LALSAIYRSG
     QRYGVGHLID LLLGRETDKI RALGHQHLTV FGKGKHLAEA DWRTLFRQLV ARGLADVDLD
     GFGGLRLTDT CRPLLRGEVN LQLRRDLKPQ RAARGSSGPS QASQLVRGDE RPLWEALRTL
     RRKLAEEHSV PPYVIFPDAT LLEMLRSQPQ SLVGMARVSG VGARKLERYG QAFLDVLTDS
     PEAPATPQPV ADLRHELVSL ARSGMTPAQI ARQLDCSEKN VYSLLAEAIA RQQLTLEEAL
     DLPEELLGEI HDAFLDGDGE LPPVAAIAEA FAARVPLGVL YCVRAALEAE LGG
//