ID   A0A1H2I1S2_9PSED        Unreviewed;       568 AA.
AC   A0A1H2I1S2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:SDU38101.1};
GN   ORFNames=SAMN05216580_2663 {ECO:0000313|EMBL:SDU38101.1};
OS   Pseudomonas guangdongensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1245526 {ECO:0000313|EMBL:SDU38101.1, ECO:0000313|Proteomes:UP000243063};
RN   [1] {ECO:0000313|Proteomes:UP000243063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCTCC 2012022 {ECO:0000313|Proteomes:UP000243063};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; LT629780; SDU38101.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2I1S2; -.
DR   STRING; 1245526.SAMN05216580_2663; -.
DR   OrthoDB; 9813348at2; -.
DR   Proteomes; UP000243063; Chromosome i.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243063}.
FT   DOMAIN          12..550
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   568 AA;  62142 MW;  F49D7E16F9AC1730 CRC64;
     MTTQVQPQSA YDVIVVGSGA GAMAAAVVAA DQGLSVLVVE KSDKYGGTSA ISGGGIWIPN
     NHYFAEKGGA DSFDKAFTYL KAAAGDKVDE ARLRAYLEYA PRMIHYLETR SRVRYAVADK
     YPDYYQHLPG SLPGGRSLDP ELFDTSLLGD EYEHMRKPSP TTLLMGRIAW TARHAHKAMS
     REFGWRLMLL GLMLRYKLDF KGRRKGKMDR RAALGASLIA ALRRSLMDRK VPLWLNTEFR
     ELVVEDGRVT GIEVLQGGRK LTLQARRGVI FGCGGFEQNQ ALREKYLPQP TRADWSATPP
     GNNTGAALEA AQAIGAATDL MDWAWWAPTI KVPGEEKPRG IFAERAFPGA IVVNGHGKRF
     VNEAAPYLEF VDAMYREHQK DSQSIPAWVI FDARFRFNYA MGPLMPAQVM PDSRLRKEWL
     NSVYWKADSL DGLARQIGVD PAGLDATVKR VNEFARTGVD SDFARGGNVF DRYYGDSNVK
     PNPCLAPLTK GPYYAMRLDA GDIGTKGGLL TDANAQVLHE NGQPIPGLYA IGNTSASVMG
     TSYPGAGGTL GPAMTFGYIA ARHIAASL
//