ID   A0A1H2KIR3_9ACTN        Unreviewed;       923 AA.
AC   A0A1H2KIR3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Regulatory protein, luxR family {ECO:0000313|EMBL:SDU68559.1};
GN   ORFNames=SAMN04488563_3883 {ECO:0000313|EMBL:SDU68559.1};
OS   Jiangella alkaliphila.
OC   Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC   Jiangella.
OX   NCBI_TaxID=419479 {ECO:0000313|EMBL:SDU68559.1, ECO:0000313|Proteomes:UP000182977};
RN   [1] {ECO:0000313|Proteomes:UP000182977}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45079 {ECO:0000313|Proteomes:UP000182977};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629791; SDU68559.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2KIR3; -.
DR   STRING; 419479.SAMN04488563_3883; -.
DR   Proteomes; UP000182977; Chromosome i.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          852..917
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          343..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        343..360
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   923 AA;  97102 MW;  E14F163E177C0E5A CRC64;
     MMDPALGLRG RHGECDVLDG LLLKARAGQS AVLVLRGEAG IGKSALLDHL LGRAAGCRVA
     RAAGSESEME LAFAGLHQLC LPFLDRLDRL PAPQHDALVT AFGLSAGRPP ERFLVGLAVL
     SLLADVAADR PLVCVVDDAQ WLDQVSLQVL AFVARRLAAE PVAMVFAVRD LDAHLELAGL
     AELTVGGLSD ADARALLDSA VPGRLDEHVR DRIVAETRGN PLALLELPRG VTAAELAGGF
     WRPDAGPLPG RIEHSFLRRV RSLPPTTQRF LLVAAAEPVG DVSLLLRATT LLELGADAAG
     AAETAGLIEL GARVRFRHPL VRSAAYRAAG SGDRREVHRA LAEATDPDAD PDRRAWHRAQ
     AAAGPDEAVA AELERSAGRA QSRGGVAAAA AFLERAAELT PDPVRRGVRA IAAARAKLRA
     GAPDTAHALL ATAQLGPLDE LHRAQVARLR AQITSVRRRG GDAVAQLLDA ARRLEPLDRA
     AARETYLEAL GAAFFAGRLG TGLPAAAAAA RAVPSGPRPP RPTDLLLDGV ATRLADGYAA
     GVPALTRALQ AFRGDDADDA VMSWLWLACP VAPEPIAPDL WDDDAWHDLA TRAVRLARGA
     GALTVLPVAL SYRAGVHLHA GEFAAAATLI EESEAIAAAT GNPPLRYTPI LLAAWRGDET
     AARAAIDAAV HEAEARGEGR ALGLAGYATA VLDNGLGHYG AALAAARTAC DYEDLGFYGW
     SLAELVEAAV RAGAPAEAGA ALELLLERAG SSGTDWALGV GARSAALLAD GERADALYRE
     AIERLGRSRA AVQQARARLL YGEWLRRENR RASAREQLRA AHETFARIGA EAFAERARRE
     LQATGETVHR RSTGSGLALT TQEAQIARLA GDGLTNPEIG AQLFISPHTV EWHLRKVFAK
     LDISSRRQLR TALPAGVRAG APV
//