ID   A0A1H2LRL3_9ACTN        Unreviewed;       246 AA.
AC   A0A1H2LRL3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Sortase A {ECO:0000313|EMBL:SDU83504.1};
GN   ORFNames=SAMN04488563_6544 {ECO:0000313|EMBL:SDU83504.1};
OS   Jiangella alkaliphila.
OC   Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC   Jiangella.
OX   NCBI_TaxID=419479 {ECO:0000313|EMBL:SDU83504.1, ECO:0000313|Proteomes:UP000182977};
RN   [1] {ECO:0000313|Proteomes:UP000182977}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45079 {ECO:0000313|Proteomes:UP000182977};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629791; SDU83504.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2LRL3; -.
DR   STRING; 419479.SAMN04488563_6544; -.
DR   OrthoDB; 5242879at2; -.
DR   Proteomes; UP000182977; Chromosome i.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05830; Sortase_E; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   InterPro; IPR042003; Sortase_E.
DR   NCBIfam; NF033747; class_E_sortase; 1.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   ACT_SITE        146
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        222
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   246 AA;  26838 MW;  289996965E4CC058 CRC64;
     MQRRAAPRHR RAARTGVPGR RTLFAAAGIA GELLLTAGAL VLLFVVYTFW GTGLQTAAAQ
     DDLRDQFQQH LLTRSDEPAE TDGAEAEPAP LELGDAYGIL RIPRFGDDWE RIVIEGTDPG
     DLKDGPGHYV DSVDPGQLGN FAVAAHRSGH GEPFAEFAEL REGDIVEMET VDGVFRYELD
     DAPGGDNDGN VIEATELWVV DPVPGEPTET EPTEARLTLT TCWPRWGSEK RMYATGVLVD
     EAPRDQ
//