ID   A0A1H2MNV5_9ACTN        Unreviewed;       334 AA.
AC   A0A1H2MNV5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=DNA-binding transcriptional regulator, LacI/PurR family {ECO:0000313|EMBL:SDU94166.1};
GN   ORFNames=SAMN04488544_2318 {ECO:0000313|EMBL:SDU94166.1};
OS   Microlunatus sagamiharensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Microlunatus.
OX   NCBI_TaxID=546874 {ECO:0000313|EMBL:SDU94166.1, ECO:0000313|Proteomes:UP000198825};
RN   [1] {ECO:0000313|Proteomes:UP000198825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21743 {ECO:0000313|Proteomes:UP000198825};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT629799; SDU94166.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2MNV5; -.
DR   STRING; 546874.SAMN04488544_2318; -.
DR   OrthoDB; 189006at2; -.
DR   Proteomes; UP000198825; Chromosome i.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR   PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:SDU94166.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198825};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          4..58
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50932"
SQ   SEQUENCE   334 AA;  35451 MW;  1C9708E6EC05A66D CRC64;
     MPRTTLKDVG ARVGVSAKTV SNVVNGTGWV TDEVADRVRA AMAELGYRPN LAARQLRSGR
     SGMIALALPQ LAQPYFAELA SQLVRAAHER GITVLIQQTD SDVEAERRIL SGIGAPAVDG
     LIMSPLTLGP ADLYARTDPT PLLLLGEQAG ASPYPHVAVD NTAAGQAATE HLLGLGRRRV
     AALGAMESEP RRAADLRLTG YRRGLEAAGL ELDERLVLPV VDYQRADGAA AARQLLESDV
     RPDAIFAFSD LLALGAMHEL LVAGVRVPED IAVIGFDDIE ESRYSTPSLS SVSPDTSSLA
     RTAVELLLAD PPVPGNHTVD FTIVERASTR RAET
//