ID A0A1H2Q1X8_9BACI Unreviewed; 370 AA.
AC A0A1H2Q1X8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=MscS family membrane protein {ECO:0000313|EMBL:SDW01147.1};
GN ORFNames=SAMN05421781_0104 {ECO:0000313|EMBL:SDW01147.1};
OS Marinococcus luteus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Marinococcus.
OX NCBI_TaxID=1122204 {ECO:0000313|EMBL:SDW01147.1, ECO:0000313|Proteomes:UP000199488};
RN [1] {ECO:0000313|EMBL:SDW01147.1, ECO:0000313|Proteomes:UP000199488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23126 {ECO:0000313|EMBL:SDW01147.1,
RC ECO:0000313|Proteomes:UP000199488};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; FNNC01000001; SDW01147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2Q1X8; -.
DR STRING; 1122204.SAMN05421781_0104; -.
DR Proteomes; UP000199488; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR045042; YnaI-like.
DR PANTHER; PTHR43634:SF2; MECHANOSENSITIVE ION CHANNEL PROTEIN 2, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43634; OW CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199488};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 146..186
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 187..253
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 260..347
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 370 AA; 42955 MW; FE2BFE2D669FF200 CRC64;
MQAYADFWME WQTRIVELPW IDIGVAVLIA LLVFAFRKLF TKYIFRFILK MTHQSRSQLF
TNVLVSFERP IRMFFAVFGI YLALLYLPIP WDSMTIINRL YGSILIVLAA WGTYKLLNTS
SMLFNPMVKR LEGKEDNMLV PFLSRVLRII IVALAFTIIL SSWGFNINGF VAGLGLGGLA
FALAAQDMVA NFIGGIIIVV ERPFKRGDWI YTPTVEGIVE DISFRSTKVR TFADSIVIVP
NNTLAHEAIT NWSEMRKREI DMTLGIEYQT PREQVLQLRE RLEEMLNNRD DIDKELILVQ
FKEFNSSSLD LWVYCFTKTT AFLEWAEIKE ELNLEIIRIL QEEGVQFAYP TQSIYIEKAS
EENYYMSDNN
//
