ID A0A1H2RS96_9GAMM Unreviewed; 647 AA.
AC A0A1H2RS96;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Diguanylate cyclase with PAS/PAC sensor {ECO:0000313|EMBL:SDW22155.1};
GN ORFNames=SAMN05443545_101392 {ECO:0000313|EMBL:SDW22155.1};
OS Aidingimonas halophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Aidingimonas.
OX NCBI_TaxID=574349 {ECO:0000313|EMBL:SDW22155.1, ECO:0000313|Proteomes:UP000198500};
RN [1] {ECO:0000313|EMBL:SDW22155.1, ECO:0000313|Proteomes:UP000198500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19219 {ECO:0000313|EMBL:SDW22155.1,
RC ECO:0000313|Proteomes:UP000198500};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FNNI01000001; SDW22155.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2RS96; -.
DR STRING; 574349.SAMN05443545_101392; -.
DR OrthoDB; 8929028at2; -.
DR Proteomes; UP000198500; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198500};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..356
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 361..431
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 434..485
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 517..647
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 647 AA; 71409 MW; 6A8A1ECFCF26DF34 CRC64;
MKWLLGTLQS RLLLGLGIGW LVLFAVGLIG ALASGSGMLT DATREHLEYE ATLIAQHVER
AVETRKSALA RLGDDIHWDD DGLHDVLANQ DGMLELFDAL AVISPQGRVV ADAPVQVGRI
GLDVTDREYF EYVRQFHDAY VSEPFIGRAT QIPLVMIAVP LETDDGEFDG MLGGVVSIQG
GTLISKLRSM RIGDEGYAAL MTASGTILNH PDESLIMQQV PGVDTHPALD LALSGWSGTA
EGELLNGQQA LQAYQQVWSA NWVVGVYLPE SQLDVMIGRF IDELWWIGAI TLALMIPVLW
ALIRGLLAPL GRLEHQIARV GRGDQSHVEL NTGMRELKEI ADTINYFVEE RRHAGLLLQD
RQAFLDAVLA SSPVGMFVCD LSGRIEYINT ALSELTGHEL EDYRRGGVIG HLHAEEFSDI
RDLWKDTLAT GREFQRQFRY FTANGELLWL EVHISLVKDG ERPRGYVGTV KDITQRREQE
AMHRWEAEHD PLTGLLNRRG FERCLADALA AWRKTTTPSV LLLFDLDHFK PINDEGGHAL
GDEMLQRIAD ALNACVRSSD SVARHGGDEF AVLMPGCNLE QAQRAAHELK QAVADVAVEH
NGKHYRVTPS MGLTALQAGD QDIDSVLARA DAASYEAKTK GRNQIVS
//
