ID   A0A1H2SMG5_9BACL        Unreviewed;       418 AA.
AC   A0A1H2SMG5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Predicted Zn-dependent peptidase {ECO:0000313|EMBL:SDW32863.1};
GN   ORFNames=SAMN05444487_102257 {ECO:0000313|EMBL:SDW32863.1};
OS   Marininema mesophilum.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC   Marininema.
OX   NCBI_TaxID=1048340 {ECO:0000313|EMBL:SDW32863.1, ECO:0000313|Proteomes:UP000198534};
RN   [1] {ECO:0000313|EMBL:SDW32863.1, ECO:0000313|Proteomes:UP000198534}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45610 {ECO:0000313|EMBL:SDW32863.1,
RC   ECO:0000313|Proteomes:UP000198534};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR   EMBL; FNNQ01000002; SDW32863.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2SMG5; -.
DR   STRING; 1048340.SAMN05444487_102257; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000198534; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198534}.
FT   DOMAIN          12..158
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          166..338
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   418 AA;  47087 MW;  ED8AF079DE3A3C00 CRC64;
     MIQKYTLPNG VRVVAESIPH VRSVAFGLWI GTGSRFEIEN KNGISHFLEH MMFKGTKTKT
     ARQLAEAFDE VGGHVNAFTS KEMTCYYAKV LDEHFEHAVD VLTDMFFEST FQMEEILKER
     KVIEEEIRMV EDTPDDIIHD WLSEAAFSRH SLGYPVLGSL ENLQTFDRET VLDYRDRYYR
     PEELVIAVAG NLPANWLAQV ETRFSHFTGK GNIEPGNTPE YTGEAIVRAK GTEQTHICLG
     LPGISLNDER IYSLILLNNL LGGNMSSRLF QEIREDRGLA YSVYSYHSAY RDSGLFTIYT
     GTGHEQAEDV IQLILNVLDS VRQDGVTANE LQKGKEQLKG SLMMSLESTN NRMSRLGKNE
     LLLGHHMTLD EVVEAVEKLT VGDILTTARA IFSKPLTLSL LSPTGKVPAT YRRNALVV
//