ID   A0A1H2WUG5_9PSEU        Unreviewed;       407 AA.
AC   A0A1H2WUG5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Precorrin-6Y C5,15-methyltransferase (Decarboxylating) {ECO:0000313|EMBL:SDW84187.1};
GN   ORFNames=SAMN05216215_1005283 {ECO:0000313|EMBL:SDW84187.1};
OS   Saccharopolyspora shandongensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=418495 {ECO:0000313|EMBL:SDW84187.1, ECO:0000313|Proteomes:UP000199529};
RN   [1] {ECO:0000313|EMBL:SDW84187.1, ECO:0000313|Proteomes:UP000199529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3530 {ECO:0000313|EMBL:SDW84187.1,
RC   ECO:0000313|Proteomes:UP000199529};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004953}.
CC   -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005879}.
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DR   EMBL; FNOK01000005; SDW84187.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H2WUG5; -.
DR   STRING; 418495.SAMN05216215_1005283; -.
DR   OrthoDB; 9787825at2; -.
DR   UniPathway; UPA00148; -.
DR   Proteomes; UP000199529; Unassembled WGS sequence.
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd11644; Precorrin-6Y-MT; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR012818; CbiE.
DR   InterPro; IPR006365; Cbl_synth_CobL.
DR   InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; TIGR02467; CbiE; 1.
DR   NCBIfam; TIGR02469; CbiT; 1.
DR   PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR   PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   PIRSF; PIRSF036428; CobL; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE   3: Inferred from homology;
KW   Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SDW84187.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDW84187.1}.
FT   DOMAIN          11..191
FT                   /note="Tetrapyrrole methylase"
FT                   /evidence="ECO:0000259|Pfam:PF00590"
SQ   SEQUENCE   407 AA;  42858 MW;  2BFCB284324F223F CRC64;
     MTVHQEKPEL VHVVGIGADG AAGLSPHARE IIDSADVLFG SSRQLDLVPE ANGQRVTWPT
     PMLPAIPGLL AEHADRSICV LASGDPMFYG VGATLVKLLG PDRVRIVPHP SSLSLACARM
     GWPLQETAAV SLVGRPVELL HPRLQPGNRL LVLSSDDGTP DEVAALLRAR GYGPSGMTVL
     SDLGGAQEGR TSSTADDWDR PASPLNVIAI ECRPAPDAKL LPSTPGLPDD AFEHDGQLTK
     RDVRAITLAR LAPTPGQLLW DVGGGAGSIA IEWMRSDPTC RAIAIEHRED RARRIATNAS
     SLGVPGLQVV AGAAPRALDG LAEPDAIFIG GGGTAPGVLE ACWAALRRGG RLVVNAVTLE
     LEVLVTDWYG RHGGELVRIS VERAAPIGGY TGWRPAMPVT QWAVSKR
//