ID A0A1H2X7A9_9GAMM Unreviewed; 353 AA.
AC A0A1H2X7A9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SDW88691.1};
GN ORFNames=SAMN05443545_103122 {ECO:0000313|EMBL:SDW88691.1};
OS Aidingimonas halophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Aidingimonas.
OX NCBI_TaxID=574349 {ECO:0000313|EMBL:SDW88691.1, ECO:0000313|Proteomes:UP000198500};
RN [1] {ECO:0000313|EMBL:SDW88691.1, ECO:0000313|Proteomes:UP000198500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19219 {ECO:0000313|EMBL:SDW88691.1,
RC ECO:0000313|Proteomes:UP000198500};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FNNI01000003; SDW88691.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2X7A9; -.
DR STRING; 574349.SAMN05443545_103122; -.
DR Proteomes; UP000198500; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12173; PGDH_4; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42789; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR PANTHER; PTHR42789:SF1; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000198500}.
FT DOMAIN 20..330
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 122..298
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 353 AA; 38007 MW; C5E205F9156AF785 CRC64;
MAFPPLPRSV IRLDVWYDPA MQAIFDQHPD YALTTIPRDA DMHSVATTLG NAHAYQISSA
KDENPTRWRA DAELLAQAPN LLCVSTSGAG YDTVDVEACT RAGVLVMNQS GANAQSVAEH
TIGLMIGVSK RLTETDRRLR RERGFTREAV MGREITGKTL GLVGLGHIGR RVAAIAQAFD
MRVIACDPAL DEATMAARGA QKVSLETLLA ESDHVSLHCP RNADTLELID AEAFRLMKPG
AVFISTARGG IHSEPALIEA LHSGHLAGAG VDVWDVEPPP LDHPLLAMPN VIATYHTAGV
THEARRNVAT WAAEQIIHTL DGGTPARLVN PDAWPSYAAR YEAIFGVRPN ASP
//
