ID A0A1H2X9R7_9PSED Unreviewed; 760 AA.
AC A0A1H2X9R7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216287_1825 {ECO:0000313|EMBL:SDW89498.1};
OS Pseudomonas kuykendallii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1007099 {ECO:0000313|EMBL:SDW89498.1, ECO:0000313|Proteomes:UP000243778};
RN [1] {ECO:0000313|Proteomes:UP000243778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-59562 {ECO:0000313|Proteomes:UP000243778};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FNNU01000002; SDW89498.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2X9R7; -.
DR STRING; 1007099.SAMN05216287_1825; -.
DR OrthoDB; 9177042at2; -.
DR Proteomes; UP000243778; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43065:SF49; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SDW89498.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000243778};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 312..363
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 398..617
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 638..755
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 344..389
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 694
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 760 AA; 81964 MW; 20F944279A16A75A CRC64;
MLGAFGHVDL GAACCGHPIV SIRFKLTLLV MAVLAPTLIA SLLAIGYVYQ DQRVRVAQSM
RETTRALALA VDRDIAQRNA IIRTLSSVPS LSLADLERFY TTARDVADSW ENSIILVDTQ
GQQLLNTRMP FGAELPHTPF LATPLDDPAA EFDVTNLYMA PIGKQYSFSV RRPIYIDGTL
RYFLSMGSFA NQINEVLVDQ NLPKGWLGTV VDGSGRIVAR NISPEAFIGK HVTGPIAEAL
GGSEEGFRET VSLDGIPLLS FYARSPESGW SVIIGLPISE VRQSAVQAMT VVGVFALLLI
GVATLLAFWV GRRITRPLRM LDATAQAMGR GEAVHPASTG MSEIDRTAAV LAQASERIQN
ASAEMSARVA AAVEQVERSQ KAMQQTQKLE ALGRLTGGIA HDFNNLLQTL TIGLQLADMA
SSDPRAKKAI EACNKSVVRG TKLTRQLMAF GRHKVEETRH VDLLQLIVEM GDLLDGALPG
RIGLTLELPE RPWPVFIDPL QCELAVLNLV FNARDAMPRG GKVTLSLAQR AVAEGEIEGL
AAGAYAELCI VDSGEGMSEE VMSKAFEPFF TTKNVGEGTG LGLAQVYGFA SQAHGTVLLQ
SAPGEGTRVR VLLPMSQEEG SVPLEAGAGP RPDVHSARVL LVDDDPLVRD VVAPALRELG
FRVEVVGNAD EALQRYRERR GGAGKPRFDI VFSDIVMPGT LDGIGLAQAL REQEPNLPIV
LATGYTERAP SDYGFTVLSK PYDVQTLVEA LRAELVRTAR
//
