ID A0A1H2YG70_9PSEU Unreviewed; 480 AA.
AC A0A1H2YG70;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SDX03838.1};
GN ORFNames=SAMN05421504_102116 {ECO:0000313|EMBL:SDX03838.1};
OS Amycolatopsis xylanica.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=589385 {ECO:0000313|EMBL:SDX03838.1, ECO:0000313|Proteomes:UP000199515};
RN [1] {ECO:0000313|EMBL:SDX03838.1, ECO:0000313|Proteomes:UP000199515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPCC 202699 {ECO:0000313|EMBL:SDX03838.1,
RC ECO:0000313|Proteomes:UP000199515};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNON01000002; SDX03838.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H2YG70; -.
DR STRING; 589385.SAMN05421504_102116; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000199515; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199515};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 480 AA; 49373 MW; 69C38EAE156F1155 CRC64;
MVSTLDRFFK ITERGSTAGR EIRGGVITFV TMAYIVVLNP LIIGSFAPDD AAAHKDVLGG
ILPVPQVAAV TALVAGVLTI LMGLVANYPF AIATGLGINS LVAVTMAPKM TWPEAMGLVV
IEGLIIVLLV FTGFRTAVFR AVPAPLKSAI AVGIGVFICL IGLVDAGFVR RLPDDAHTTV
PVGLGIGGSI ASWPTAVFVV GLLVTGILVA KRVKGGILIG VLVTTVLAIV VETIVKAGPS
KGTNPKGWNL GYPALPDQVV GLPDLSLVGD VSFGAWTRLP IITVVLFVFT LVLADFFDAM
GTMTGLGKEA GLVGKDGQLP NIGKALFVEG LAGAAGGLGS ASSNTVFVES ASGIAEGART
GLANVVTGVL FLAAMFFTPL YQVVPVEAAA PALVVVGALM MSQVKDIDFT DFSIALPAFL
TIVVMPFTYS IANGIGAGFI SYVAIRAVTG KARGVHPLMW LIAVAFVAYF AVGPIQDALR
//
