ID   A0A1H3A6C2_9RHOB        Unreviewed;       317 AA.
AC   A0A1H3A6C2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:SDX24734.1};
GN   ORFNames=SAMN05444336_10460 {ECO:0000313|EMBL:SDX24734.1};
OS   Albimonas donghaensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Albimonas.
OX   NCBI_TaxID=356660 {ECO:0000313|EMBL:SDX24734.1, ECO:0000313|Proteomes:UP000199118};
RN   [1] {ECO:0000313|EMBL:SDX24734.1, ECO:0000313|Proteomes:UP000199118}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17890 {ECO:0000313|EMBL:SDX24734.1,
RC   ECO:0000313|Proteomes:UP000199118};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC       family. {ECO:0000256|ARBA:ARBA00010398}.
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DR   EMBL; FNMZ01000004; SDX24734.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H3A6C2; -.
DR   STRING; 356660.SAMN05444336_10460; -.
DR   OrthoDB; 9803687at2; -.
DR   Proteomes; UP000199118; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR   PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   3: Inferred from homology;
KW   Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SDX24734.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199118};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SDX24734.1}.
FT   DOMAIN          21..280
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
FT   REGION          293..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   317 AA;  34258 MW;  6ED39FDFBB943681 CRC64;
     MTRTIVESKS KTVVIGFDEP FCVIGERINP TGRKKLAAEL EMDDFSTVEK DAAEQVACGA
     MILDINSGAV FSNRMEADPR YADNNFVEPM LMKALIERVQ AIVDVPLCID SSVPGALENG
     LEAAEGRPLL NSVTGEEERM ELVLPLVRKY NVPVVAISND DTGISEDPEI RFAVAKKIVE
     RAADFGIPAH DIVVDPLVMP IGAMATAGKQ VFALVRRLRD ELGVNTTCGA SNVSFGLPNR
     HGINAAFLPM AITAGMTSAI MNPVRPQEMN AIRAANLLMN NDPHGMAWIQ ANREPTPEGE
     APAGARGARE GRRRRRG
//