ID A0A1H3AI29_9RHOB Unreviewed; 397 AA.
AC A0A1H3AI29;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Membrane fusion protein, multidrug efflux system {ECO:0000313|EMBL:SDX29362.1};
GN ORFNames=SAMN05444336_104199 {ECO:0000313|EMBL:SDX29362.1};
OS Albimonas donghaensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Albimonas.
OX NCBI_TaxID=356660 {ECO:0000313|EMBL:SDX29362.1, ECO:0000313|Proteomes:UP000199118};
RN [1] {ECO:0000313|EMBL:SDX29362.1, ECO:0000313|Proteomes:UP000199118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17890 {ECO:0000313|EMBL:SDX29362.1,
RC ECO:0000313|Proteomes:UP000199118};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FNMZ01000004; SDX29362.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3AI29; -.
DR STRING; 356660.SAMN05444336_104199; -.
DR OrthoDB; 9816569at2; -.
DR Proteomes; UP000199118; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000199118};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..397
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011558488"
FT DOMAIN 67..298
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 299..366
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT COILED 102..129
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 397 AA; 41208 MW; 4399A01D97585FDA CRC64;
MKPFRYAAPA AALLAALLLA GCDDDQANGA PAAGGGGGRP PSPVAVIEAT PAAIPLVNEL
PGRIAPTRIA EVRPRVSGIL VERVFEQGSV VEAGDVLYRI DSDQFRVQVE RAEALLDQAE
ATRKAASQSA ARQVELRERN VVSAQAFDDA NAALAVAEAG VAVARAALAA AQLDLQHADV
RAPIAGRIGR ARVTEGALVT ANAVDSLATI QQLDPVYADF TQSAADLMAL RRAHENGGLT
RSETGEAQVR LLLDDGSEYA HDGKLLFTEA TVDASTGQII LRGEFPNPDG DLLPGMYVRV
LIEQGVQTNA LAVPVQAVQR DMGGKPQLYV VGPEGRAQVR PVTAGRVVGD LWVIEQGLNP
GDKVIVEGFQ KIGPGAPVAA EPWSGGATAA ARTADAG
//
